نتایج جستجو برای: quinoline alkaloids

تعداد نتایج: 18029  

2012
Agnieszka Skórska-Stania Magdalena Jezierska-Zięba Barbara Kąkol Michał Fedoryński Barbara J. Oleksyn

The title compound {systematic name: 1-(2-bromo-benz-yl)-5-ethenyl-2-[hy-droxy(quinolin-4-yl)meth-yl]-1-aza-bicyclo-[2.2.2]octan-1-ium bromide}, C(26)H(28)BrN(2)O(+)·Br(-), is a chiral quater-nary ammonium salt of one of the Cinchona alkaloids. The planes of the quinoline and of the bromo-benzyl substituent are inclined to one another by 9.11 (9)°. A weak intra-molecular C-H⋯O hydrogen bond occ...

Journal: :Plant physiology 2004
Yasuyo Yamazaki Mariko Kitajima Masanori Arita Hiromitsu Takayama Hiroshi Sudo Mami Yamazaki Norio Aimi Kazuki Saito

Camptothecin derivatives are clinically used antitumor alkaloids that belong to monoterpenoid indole alkaloids. In this study, we investigated the biosynthetic pathway of camptothecin from [1-13C]glucose (Glc) by in silico and in vivo studies. The in silico study measured the incorporation of Glc into alkaloids using the Atomic Reconstruction of Metabolism software and predicted the labeling pa...

Journal: :Journal of Chemistry 2021

The recent outbreak of the highly contagious coronavirus disease 2019 (COVID-19) caused by novel SARS-CoV-2 has created a global health crisis with socioeconomic impacts. Although, recently, vaccines have been approved for prevention COVID-19, there is still an urgent need discovery more efficacious and safer drugs especially from natural sources. In this study, number quinoline quinazoline alk...

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