نتایج جستجو برای: quic root

تعداد نتایج: 139075  

2016
Lynne I. McGuire Anna Poleggi Ilaria Poggiolini Silvia Suardi Katarina Grznarova Song Shi Bart de Vil Shannon Sarros Katsuya Satoh Keding Cheng Maria Cramm Graham Fairfoul Matthias Schmitz Inga Zerr Patrick Cras Michele Equestre Fabrizio Tagliavini Ryuichiro Atarashi David Knox Steven Collins Stéphane Haïk Piero Parchi Maurizio Pocchiari Alison Green

Real-time quaking-induced conversion (RT-QuIC) has been proposed as a sensitive diagnostic test for sporadic Creutzfeldt-Jakob disease; however, before this assay can be introduced into clinical practice, its reliability and reproducibility need to be demonstrated. Two international ring trials were undertaken in which a set of 25 cerebrospinal fluid samples were analyzed by a total of 11 diffe...

2016
Graham Fairfoul Lynne I. McGuire Suvankar Pal James W. Ironside Juliane Neumann Sharon Christie Catherine Joachim Margaret Esiri Samuel G. Evetts Michal Rolinski Fahd Baig Claudio Ruffmann Richard Wade‐Martins Michele T. M. Hu Laura Parkkinen Alison J. E. Green

We have developed a novel real-time quaking-induced conversion RT-QuIC-based assay to detect alpha-synuclein aggregation in brain and cerebrospinal fluid from dementia with Lewy bodies and Parkinson's disease patients. This assay can detect alpha-synuclein aggregation in Dementia with Lewy bodies and Parkinson's disease cerebrospinal fluid with sensitivities of 92% and 95%, respectively, and wi...

Journal: :SN Computer Science 2021

2016
Nicholas J. Haley Scott Carver Laura Hoon-Hanks Davin M. Henderson Kristen A. Davenport Elizabeth Bunting Shawn Gray Judith Galeota Ivy LeVan Tracy Dubovos Paul Shelton Edward A. Hoover Bruce Trindle

Chronic wasting disease detection in the lymph nodes of free-ranging cervids by real time quaking-induced conversion" (2014). Abstract 23 Chronic wasting disease (CWD), a transmissible spongiform encephalopathy of deer, elk 24 and moose, is the only prion disease affecting free-ranging animals. First identified in northern 25 Colorado and southern Wyoming in 1967, new epidemic foci of the disea...

Journal: :Proceedings on Privacy Enhancing Technologies 2023

Website fingerprinting (WF) is a well-known threat to users' web privacy. New Internet standards, such as QUIC, include padding support defenses against WF. Previous work on QUIC WF only analyzes the effectiveness of when users are behind VPN. Yet, this not how most browse Internet. In paper, we provide comprehensive evaluation QUIC-padding-based directly web, i.e., without VPNs, HTTPS proxies,...

Journal: :Journal of Network and Systems Management 2022

New services with low-latency (LL) requirements are one of the major challenges for envisioned Internet. Many optimizations targeting latency reduction have been proposed, and among them, jointly re-architecting congestion control active queue management (AQM) has particularly considered. In this effort, Low Latency, Loss Scalable Throughput (L4S) proposal aims at allowing both Classic LL traff...

Journal: :International Journal of Information Security 2022

Abstract Built on top of UDP, the recently standardized QUIC protocol primarily aims to gradually replace TCP plus TLS HTTP/2 model. For instance, HTTP/3 is designed exploit QUIC’s features, including reduced connection establishment time, multiplexing without head line blocking, always-encrypted end-to-end security, and others. This work serves two key objectives. Initially, it offers first ou...

2015
Kazunori Sano Ryuichiro Atarashi Noriyuki Nishida

A major unsolved issue of prion biology is the existence of multiple strains with distinct phenotypes and this strain phenomenon is postulated to be associated with the conformational diversity of the abnormal prion protein (PrP(Sc)). Real-time quaking-induced conversion (RT-QUIC) assay that uses Escherichia coli-derived recombinant prion protein (rPrP) for the sensitive detection of PrP(Sc) re...

Niti Kiran Raageeva Bimal

In vitro propagation of rose (Rosa indica) as well as rose breeding is a valuable economic enterprise and has received highest importance globally including Indian subcontinent. The development of new cultivars for commerce is faced with new challenges. In vitro micropropagation protocols of varieties of roses have been established but very few reports on the clonal propagation of local cultiva...

Journal: :Global heart 2015
Colleen Barbero Siobhan Gilchrist Michael W Schooley Jamie F Chriqui Douglas A Luke Amy A Eyler

An essential strategy expected to reduce the global burden of chronic and cardiovascular disease is evidence-based policy. However, it is often unknown what specific components should constitute an evidence-based policy intervention. We have developed an expedient method to appraise and compare the strengths of the evidence bases suggesting that individual components of a policy intervention wi...

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