A broad and simple method permitted halide ions in quaternary heteroaromatic and ammonium salts to be exchanged for a variety of anions using an anion exchange resin (A(-) form) in non-aqueous media. The anion loading of the AER (OH(-) form) was examined using two different anion sources, acids or ammonium salts, and changing the polarity of the solvents. The AER (A(-) form) method in organic s...

Quaternary ammonium salts are frequently used as antibacterial agent that disrupts cell membrane through the binding of their ammonium cations to anionic sites in the outer layer tissue of bacteria. This article describes the synthesis of quaternary ammonium salt-type antibacterial agents with a phosphate group that strongly binds to hydroxyapatite and bromide ion as counterion. Evaluation of t...

A systematic approach was used to evaluate the electrospray ionization mass spectral (ESI-MS) analysis of sucrose octasulfate (SOS), an important pharmaceutical agent. SOS represents a model for other suffated carbohydrates, such as heparin and glycosaminoglycan-derived oligosaccharides that also are highly sulfated and pose difficult analytical problems. A survey of ammonium counterions showed...

The pharmacological properties of tertiary sulphonium salts appear to be similar to those of quaternary ammonium salts. The trimethyl+ sulphonium ion, Me3S, resembles the tetramethyl+ ammonioum ion, Me N in its ability to paralyse the frog sartorius preparation (Ing and Wright, 1933): decamethylene bisdimethylsulphonium + + Me2S-(CH2)10-SMe2, resembles decamethonium, + + Me3N-(CH2)0-NMe3, in it...

A novel method with quaternary ammonium salts as internal additives has been applied to the mass scale calibration of time-of-flight secondary ion mass spectrometry (TOF-SIMS). Five kinds of quaternary ammonium salts, octyltrimethylammonium bromide (C8TMA), tetradecyltrimethylammonium chloride (C14TMA), octadecytrimethylammonium chloride (C18TMA), cetylpyridinium chloride (CPC) and benzyldimeth...

The microwave synthesis of twenty quaternary ammonium salts is described. The syntheses feature comparable yields to conventional synthetic methods reported in the current literature with reduced reaction times and the absence of solvent or minimal solvent.

Calix[4]arene derivatives supported on monolayer protected gold clusters show a remarkable enhanced binding efficiency towards quaternary ammonium salts in homogeneous solution of apolar solvents with respect to the corresponding unsupported hosts.