Quadruple mutations in the Plasmodium falciparum dihydrofolate reductase (PFDHFR) enzyme give rise to the highest level of pyrimethamine resistance leading to treatment failures. We describe here the presence of these quadruple mutations in a majority of P. falciparum isolates from Car Nicobar (Andaman and Nicobar) Island, India. Isolates from the mainland, however, continue to show a prevalenc...

The thesis, together with its practice-research works, presents an objectoriented perspective on the JPEG standard. Using the object-oriented philosophy of Graham Harman as a theoretical and also practical starting point, the thesis looks to provide an account of the JPEG digital object and its enfolding within the governmental scopic regime. The thesis looks to move beyond accounts of digital ...

The Reduced Wall Acetylation (RWA) proteins are involved in cell wall acetylation in plants. Previously, we described a single mutant, rwa2, which has about 20% lower level of O-acetylation in leaf cell walls and no obvious growth or developmental phenotype. In this study, we generated double, triple, and quadruple loss-of-function mutants of all four members of the RWA family in Arabidopsis (A...

A D(−1)-quadruple is a set of positive integers {a, b, c, d}, with a < b < c < d, such that the product of any two elements from this set is of the form 1+n2 for some integer n. Dujella and Fuchs showed that any such D(−1)-quadruple satisfies a = 1. The D(−1) conjecture states that there is no D(−1)-quadruple. If b = 1+ r2, c = 1+ s2 and d = 1+ t2, then it is known that r, s, t, b, c and d are ...

in this paper, lagrangian and equations describing one-dimensional anisotropic non-heisenberg model are studied. in this study we used the generalized coherent states in real parametrizations and the feynman path integral for these states in su(3) group. these equations describe nonlinear dynamics of non-heisenberg ferromagnetic chain completely. solutions of these equations are magnetic solito...

telenomus beneficiens is a common egg parasitoid of sugarcane top borer scirpophaga excerptalis; however, in winter time the incidence of the parasitoid on top borer eggs is extremely low. t. beneficiens adults were released at various time durations into sugarcane plots to evaluate the parasitic potentiality of the parasitoid against sugarcane top-borer. the egg parasitoid t. beneficiens of su...

background: several large clinical trials and meta-analyses have shown about 20% failure to eradicate helicobacter pylori ( h. pylori ), necessitating investigations for second-line treatments. the aim of this study was to evaluate the effects of clarithromycin-containing quadruple regimen after nitroimidazole-containing quadruple therapy failure. methods: thirty two patients who had failed 10-...