A wide range of vinyl sulfone-modified carbohydrates have been prepared as starting materials for the synthesis of polysubstituted chiral pyrroles. All these vinyl sulfones reacted efficiently with ethylisocyanoacetate to generate a plethora of new pyrrole derivatives. Furanosyl rings opened up during pyrrole synthesis, and pyranosyl rings were opened up by reacting the pyrrole with POCl(3)/DMF...

One-step reactions between squaric acid and pyrroles, such as 3-ethyl-2,4-dimethyl-pyrrole 1,2,5-trimethylpyrrole, in water provide the corresponding pyrrol-2-yl- pyrrol-3-yl-containing semisquaraines high yields. These serve useful precursors for synthesis of various non-symmetric pyrrole-containing squaraine dyes.

The cyclocondensation of enones with aminoacetonitrile furnishes 3,4-dihydro-2H-pyrrole-2-carbonitriles which can be readily converted to 2,4-disubstituted pyrroles by microwave-induced dehydrocyanation. Alternatively, oxidation of the intermediates produces 3,5-disubstituted pyrrole-2-carbonitriles.

We report the synthesis and characterization of the pyrrole sulfonamide as a new class of potential molecular receptors, including conformational analysis and molecular recognition studies for four pyrrole sulfonamide derivatives.

i The thesis entitled “Uses of Pyrrole Amino Acid based Scaffolds in Peptidomimetics and Studies Directed Towards the Total Synthesis of Antascomicin A”, consists of three chapters: CHAPTER I: Deals with the synthesis and conformational studies of pyrrole amino acid based peptidomimetics. This chapter is divided into two parts: Part A: Describes the synthesis and conformational studies of linea...

Boc-protected benzimidazole-pyrrole, benzimidazole-imidazole, and benzimidazole-methoxypyrrole amino acids were synthesized and incorporated into DNA binding polyamides, comprised of N-methyl pyrrole and N-methyl imidazole amino acids, by means of solid-phase synthesis on an oxime resin. These hairpin polyamides were designed to determine the DNA recognition profile of a side-by-side benzimidaz...

The title pyrrole derivative, C(12)H(17)NO(4), consists of a pyrrole ring with two diagonally attached meth-oxy-carbonyl groups and two diagonally attached ethyl groups. The two carbonyl groups are approximately in the same plane as the pyrrole ring, making dihedral angles of 3.50 (19) and 6.70 (19)°. In the crystal, adjacent mol-ecules are assembled into dimers in a head-to-head mode by pairs ...

Coal is a major contributor to the global emission of nitrogen oxides (NOx). The NOx formation during coal utilization typically derives from the thermal decomposition of N-containing compounds (e.g., pyrrolic groups). NH₃ and HCN are common precursors of NOx from the decomposition of N-containing compounds. The existence of H₂O has significant influences on the pyrrole decomposition and NOx fo...

Tetraarylpyrroles with a 1-azulenyl substituent were prepared by the reaction of 1-azulenyl ketones, which have various aryl-substituents at their α-position, with benzoin in the presence of ammonium acetate as a nitrogen source of the pyrrole ring. Optical property of the tetraarylpyrroles obtained by the reaction was clarified by UV/Vis spectroscopy and/or time-dependent density functional th...