نتایج جستجو برای: pyrimidine quinoxalines

تعداد نتایج: 10165  

Journal: :Chemical communications 2014
Zhi-Jun Yang Chuan-Zhuo Liu Bo-Lun Hu Chen-Liang Deng Xing-Guo Zhang

A novel one-pot strategy for the synthesis of 3-trifluoromethylquinoxalines from N-aryl enamines and nitromethane was developed. The tandem reaction is achieved through nitrosation of alkenes, tautomerization and cyclization, which can be applicable to a wide range of enamines with excellent functional group tolerance and afford quinoxalines in moderate to good yields.

Journal: :Antimicrobial agents and chemotherapy 2010
Jingjing Zhao Zhangliu Chen Sheng Chen Yuting Deng Yahong Liu Wei Tian Xianhui Huang Congming Wu Yongxu Sun Yan Sun Zhenling Zeng Jian-Hua Liu

OqxAB has recently been identified as one of the mechanisms of plasmid-mediated quinolone resistance (PMQR). Compared to what is observed for other PMQR determinants, there is a paucity of data with regard to the prevalence and epidemiology of OqxAB and its contribution to resistance to different antimicrobials. In this study, the prevalence and dissemination of oqxAB and other PMQR genes in Es...

Journal: :Biochemistry & Pharmacology: Open Access 2014

Journal: :Chemical communications 2014
K K Durga Rao Viswanadham Muktapuram Prathap Reddy Pochampalli Sathyanarayana Owk Ravi Ruchir Kant Surendar Reddy Bathula

An efficient iodine-mediated oxidative annulation of aryl acetylenes-arylethenes-aromatic ketones with 1,2-diamines for the synthesis of pyrazines and regioselective synthesis of quinoxalines is presented. A multipathway coupled domino approach has been developed for the one-pot synthesis of 1,4-diazines with high functional group compatibility.

Journal: :Chemical and Pharmaceutical Bulletin 1958

2014
KUO CHU HWANG PERIYASAMY MURUGAN

This paper reports the synthesis of nitrogen containing heterocyclic compounds such as quinoxalines (5-7), imidazoles (8, 9,10,11), aminothiazole (12), aminooxazole (13), aminoimidazole (14) and benzothiazine (17) from the reaction with unsymmetrical diketone 4, 3 and 4a respectively. The aforementioned compounds with 4-pyridyl,4fluorophenyl groups have different positions in their ring skeleto...

Journal: :ACS combinatorial science 2011
Li-Hsun Chen Chia-Mao Chang Deepak B Salunke Chung-Ming Sun

Diversity-oriented synthesis of novel benzimidazole linked indolo-benzodiazepine/quinoxaline ring systems using poly(ethylene glycol) as soluble polymer support is described. Commercially available 4-fluoro-3-nitrobenzoic acid and indoline were utilized for the construction of these annulated biheterocyclic compound libraries having multiple privileged structures with three-point structural div...

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