Abstract Culture supernatants of Basfia succiniciproducens derived from the industrial production succinic acid exhibit an intense nutty, root vegetable‐like, buttery and sourish smell. By means headspace‐gas chromatography‐mass spectrometry‐olfactometry (HS‐GC‐MS‐O), 14 odour‐active compounds were perceived identified using two GC‐columns different polarity comparison retention indices mass sp...

A transition metal free tandem two-step strategy has been developed involving hydrolysis of 2-chloro-3-alkynyl quinoxalines/pyrazines followed by in situ cyclization of the corresponding 2-hydroxy-3-alkynyl intermediates in a single pot leading to fused furo N-heterocycles as potential inhibitors of sirtuins. A representative compound showed promising pharmacological properties in vitro and in ...

In this paper, calcium iodate nanoparticles were first synthesized by the modified reaction of Ca(NO3)2 and KIO3 in an aqueous medium under ultrasonic irradiation. The structure nanocatalyst was then characterized FT-IR, FESEM, EDX, XRD, BET techniques. Afterward, fabricated Ca(IO3)2 applied as a facile synthesis heterocycles including quinoxalines, 5,6-dicyano pyrazines, pyrido[2,3-b]pyrazines...

We report a general and facile method that provides rapid entry into 3-aryl substituted 4,5,6,7-tetrahydro[1,2,3]triazolo[1,5-a]pyrazines and their ring fused analogues in one-pot under palladium-copper catalysis. The methodology utilises simple and easily available substrates of broad range. The applicability of this reaction for the synthesis of optically active products has been demonstrated...

An efficient, general and practical synthesis of diverse 3,4-dihydropyrazines, 6,7-dihydro-[1,2,3]triazolopyrazines and 7,8-dihydro-[1,2,3]triazolodiazepines through intramolecular 1,3-dipolar cycloaddition from amino acid derived common intermediates with high yields is described. Moreover, one-pot access to optically active 3-aryl substituted 6,7-dihydro-[1,2,3]triazolo[1,5-a]pyrazines in the...