Detailed safety review of the intestinal anthelminthics (pyrantel and niclosamide) and antischistosomal and antitrematodes (oxamniquine and triclabendazole) was conducted using publications in journals and major reference sources combined with the assessment of adverse drug reaction (ADR) reports in the database of the WHO Collaborating Centre for International Drug Monitoring in Sweden. Data f...

Canine heartworm disease is caused by infection with Dirofilaria immitis, a filarial nematode that resides in the pulmonary arteries and occasionally in the right heart chambers of infected dogs. Here the authors evaluated the effect of a combination of doxycycline (10 mg/kg/sid for 30 days) and ivermectin–pyrantel(6μg/kg [DOSAGE ERROR CORRECTED] of ivermectin+5mg/kg of pyrantel every 15 days f...

Abdominal and cerebral angiostrongyliasis are two important infections produced by metastrongylid worms, the former occurring in Central and South America and the later in Asia and Pacific Islands. Drug treatment is a challenge since the worms and its evolving larvae live or migrate inside vessels and efficient killing of the parasites may produce more severe lesions. Larvicidal effect of certa...

Materials and methods Parasiticidal effect: Small pigmented eels infected by a mixed population of Pseudodactylogyrus bini and P. anguillae, app. 3 weeks post-infection, were exposed to different concentrations of ivermectin (Ivomec, injectable), pyrantel citrate (BanminthR vet.) and morantel tartrate (Table 1). Exposure was conducted as waterbath treatments for 24 h at 25°C in 7 I aerated drug...

The effect of an administration of Bi 58 Nowy (38% dimethoate) and/or pyrantel embonate on the activity of superoxide dismutase (SOD) and catalase (CAT) in erythrocytes and on malondialdehyde (MDA) concentration in rat liver homogenates was investigated. Bi 58 Nowy was administered for 4 weeks with drinking water at a dose of 15.48 mg/kg b.w. (1/25 LD50). Pyrantel embonate was given with a stom...

Experiments were carried out in the hamster to compare the relative susceptibility of Necator americanus and Ancylostoma ceylanicum to treatment with ivermectin. A. ceylanicum was found to be 300 times more sensitive to the anthelmintic with a 50% effective dose (ED50) of the order of 10-15 micrograms kg-1 body weight whilst that for N. americanus approximated to 3-5 mg kg-1. Furthermore, where...

Received: Revised: Accepted: 2013–11–17 2014–02–28 2014–03–04 The study was conducted to determine the infection rate of helminths in peafowls and to evaluate the comparative efficacy of two broad spectrum anthelmintics. For this purpose, fecal samples of 87 different breeds of peafowls were collected and tested for the presence of helminths. Fecal samples were examined by direct smear and cent...

Abstract. Widiyono I, Rusmihayati, Purnamaningsih H, Sahara A. 2023. Zoonotic gastrointestinal nematodes in pet cats Yogyakarta (Indonesia) and their susceptibility to anthelmintics. Biodiversitas 24: 3332-3337. Domestic (Felis catus Linnaeus, 1758), which live close humans, can host some zoonotic nematodes. Therefore, a study on domestic anthelmintic resistance is essential for controlling pre...

BACKGROUNDS: Occurrence of resistance against antiparasitic drugs has made it essential for researchers to find new sources for antiparasitic drugs. OBJECTIVES: This study was performed to determine the efficiency of alcoholic extract of worm wood (Artemisia absinthium) on Syphasia parasite. METHODS: Artemisia absinthium extract was examined on 3 groups of mice at 2.5%, 5% and 10% concentration...