نتایج جستجو برای: pulmonary fibrosis
تعداد نتایج: 305749 فیلتر نتایج به سال:
Multiple investigators have undertaken genetic studies in idiopathic pulmonary fibrosis populations in attempts to define genetic links to disease in hopes that this would improve understanding of disease pathogenesis and target pathways for therapy. Multiple genes have been evaluated using a candidate gene approach with limited success, with results suggesting a disease modifier effect rather ...
the technique of transbronchial lung biopsy (tblb) has expanded the diagnostic yield of bronchoscopy . in this article we are presenting 54 patients with diffuse pulmonary parenchymal involvement who underwent this procedure during six years between june 1980 and december 1989. the diagnostic yield of this technique in diffuse pulmonary parenchymal disease is great and was 66 percent excluding ...
context cystic fibrosis (cf) is the most widespread autosomal recessive genetic disorder that limits life expectation amongst the caucasian population. as the median survival has increased related to early multidisciplinary intervention, other manifestations of cf have emergedespecially for the broad spectrum of hepatobiliary involvement. the present study reviews the existing literature on liv...
Fibrosis is the pathological condition resulting in the growth of excess fibrous connective tissue in an organ or body system as a reparative or reactive process. In the field of clinical pathology, clinicians and medical scientists are endeavoring to translate experimental knowledge into effective, innovative treatments for a range of fibrotic conditions. The amelioration of whole organ functi...
More complex in vitro models are needed to advance treatments of pulmonary fibrosis.
Recent epidemiological studies have suggested an increased risk of venous thromboembolism (VTE) in lung fibrosis. Large-scale epidemiological data regarding the risk of VTE in pulmonary fibrosis-associated mortality have not been published. Using data from the National Center for Health Statistics from 1988-2007, we determined the risk of VTE in decedents with pulmonary fibrosis in the USA. We ...
Pulmonary alveolar proteinosis (PÂP) is a rare pulmonary disease and is rarer in children in which abnormal accumulation of surfactant in alveoli, causes pulmonary signs and symptoms which gradually progresses to pulmonary fibrosis and respiratory insufficiency. There are some modalities for treatment of PÂP but its only effective treatment method, is whole lung lavage (WLL) under general Âne...
Background: Bleomycin-induced lung fibrosis has been accepted as an animal model for fibrosis in rats. The aim of this study was to evaluate the effects of saffron aqueous extract on this disorder paving the way for more investigation in treating idiopathic pulmonary fibrosis in human. Methods: Male Wistar rats (250–300 gr) were instilled a single dose of bleomycin (5 mg/kg) via in...
Molecular screening of R117H mutation in non caucasian cystic fibrosis patients in the north of Iran
Cystic fibrosis is an autosomal recessive disease caused by a wide spectrum of mutations in the gene encoding for the cystic fibrosis transmembrane conductance regulator protein. These mutations that correlate with different phenotypes, vary in their frequency and distribution in different populations. In this study missense mutation R117H that associated with the different clinical symptoms wa...
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