The legislation to make stringent provision for the control and regulation of operations relating to narcotic drugs and psychotropic substances, has been enforced since September 1985. Since mental health professionals have to deal with the prescription 0 f psychotropic medications and also deal with the rising number of cases of drug dependence and abuse, it is important for all psychiatrists ...

CEBRID (Brazilian Center of Information on Psychotropic Drugs) conducted two household surveys on drug use in Brazil, the first in 2001 and the second in 2005, making it possible for researchers, for the first time ever, to have a timeline comparison using this type of methodology. The universe studied corresponded to the Brazilian population living in 107 Brazilian cities with more than 200.00...

The liver is the organ by which the majority of substances are metabolized, including psychotropic drugs. There are several pharmacokinetic changes in end-stage liver disease that can interfere with the metabolization of psychotropic drugs. This fact is particularly true in drugs with extensive first-pass metabolism, highly protein bound drugs and drugs depending on phase I hepatic metabolic re...

Many commonly used drugs, with each causing changes that may be potentially lethal, can adversely affect the function of the heart. In addition some drugs have synergistic effects that can also damage cardiovascular tissues. The drug-related cardiotoxic effects of antineoplastic agents, psychotropic medications, heavy metals, substances of abuse, promotility agents, antihistamines, antimicrobia...

Introduction : Rhabdomyolysis is characterized by a muscle injury that leads to the release of intracellular contents/constituents into systemic circulation. Aim We examined association between severity clinical presentation and creatinine phosphokinase values in patients with rhabdomyolysis acutely intoxicated psychotropic chemical substances. Materials methods This clinically controlled prosp...

Data on psychopharmacological treatment of individuals with autism spectrum disorder (ASD) are scarce, especially for European countries. This study evaluated psychopharmacotherapy utilisation in children and adolescents with a diagnosis of ASD in Germany. Data of a large statutory health insurance company were analysed and outpatients aged 0-24 years with a diagnosis of ASD during a 1-year-per...

Thirty-two psychotropic substances (31 compounds and one plant) have been controlled as designated substances (Shitei-yakubutsu) in Japan by the Pharmaceutical Affairs Law since April 2007. Although the trafficking of these drugs has decreased because of this regulation, new designer drugs (synthetic cannabinoids and cathinones) have appeared, one after the other. As of October 2011, 40 compoun...

BACKGROUND Development of pharmacological treatment in mental disorders has risen drastically over the past decade in Taiwan. We performed a survey of the National Health Insurance claims for outpatient psychiatric services to study the utilization of psychotropic drugs. The analysis followed the drug classification and standardized measurements proposed by the World Health Organization. METH...

Multidisciplinary forensic and pharmaceutical, organizational legal, technological study of alcohol-containing liquids as factors in the formation development polydrug addiction among public population Ukraine was conducted. Determined that combined intake several psychoactive substances leads to new variants addiction. Noted substances, main are containing ethyl alcohol. Classification stages ...

BACKGROUND Polydrug abuse is a known problem among opioid-dependent patients receiving opioid maintenance treatment (OMT). However, improved laboratory diagnostics is required to reveal polydrug abuse in its current scope. Furthermore, there are few studies focusing on the relationship between polydrug abuse and adequacy of the dose of OMT medicine. This study aimed to evaluate the polydrug abu...