Pharmacognosy Research,2022,14,4,429-441.DOI:10.5530/pres.14.4.63Published:October 2022Type:Original ArticleAuthors:Vidhi Bhatia, and MS Arohi Paul Author(s) affiliations: Vidhi Bhatia*, Vivekanand Education Society’s College of Pharmacy Chembur, Mumbai, Maharashtra, INDIA. Abstract:Background: Self-emulsifying drug delivery system (SEDDS) solid-SEDDS Boswellia serrata extract (BSE) was aimed a...

The objective of this study was to design and develop o/w microemulsion for transdermal delivery of poorly water soluble acyclovir by aqueous titration method. Oleic acid: castor oil (3:1), tween 80, and ethanol were selected as oily phase, surfactant and cosurfactant respectively. The Pseudoternary phase diagrams were constructed by aqueous titration method. The cosurfactant affect the shape a...

We review our work on combinatorial search and investigation of morphotropic phase boundaries (MPBs) in chemically substituted BiFeO3 (BFO). Utilizing the thin-film composition spread technique, we discovered that rare-earth (RE 5 Sm, Gd, and Dy) substitution into the A-site of the BFO lattice results in a structural phase transition from the rhombohedral to the orthorhombic phase. At the struc...

Cinnamon leaf oil contains a high percentage of eugenol and has antimicrobial, antioxidant and antiinflammatory properties. However, the undiluted oil can cause irritation to the skin. Therefore, the aims of this study were to develop and evaluate cinnamon leaf oil nanocream using palm oil. Nanocream base was prepared using different ratios of oil, surfactants and water. The surfactant used wer...

The aim of the present study was to investigate the potential of a nanoemulsion formulation for topical delivery of aceclofenac. Various oil-in-water nanoemulsions were prepared by the spontaneous emulsification method. The nanoemulsion area was identified by constructing pseudoternary phase diagrams. The prepared nanoemulsions were subjected to different thermodynamic stability tests. The nano...

The objective of this work was to prepare an oil/water glimepiride (GM) microemulsion (ME) for oral administration to improve its solubility and enhance its bioavailability. Based on a solubility study, pseudoternary phase diagrams, and Box-Behnken design, the oil/water GMME formulation was optimized and prepared. GMME was characterized by dynamic laser light scattering, zeta potential, transmi...

Alpinia galanga oil (AGO) possesses various activities but low aqueous solubility limits its application particularly in aquatic animals. AGO has powerful activity on fish anesthesia. Ethanol used for enhancing water miscible of AGO always shows severe side effects on fish. The present study explores the development of self-microemulsifying drug delivery systems (SMEDDS) and nanoemulsions (NE) ...

Atorvastatin, a highly lipophilic anti-hyperlipidemic drug, has poor oral bioavailability (14%) due to hepatic first pass effect. The present study aimed at developing an optimal oral nanoemulsion formulation containing an atorvastatin using different proportions of oil and surfactant systems for enhancing its oral bioavailability. Pseudoternary phase diagrams were constructed by aqueous titrat...