The objective of the study was to describe clinical, imaging, surgical and histological findings in a dog with Rathke's cleft cyst pituitary gland. A 6-year-old, female, neutered Staffordshire bull terrier presented an acute onset abnormal behaviour. Magnetic resonance imaging skull showed mass 12.9 mm (height) × 8.8 (width) 10.2 (length) height/brain area value 0.73 (reference <0.31). were sug...

BackgroundCleft lip and cleft palate (also, known as or facial clefts), are amongst the most common congenital deformities affecting the jaw and face as well as the most common defects associated with lip and palate. Thus, the current study was an attempt to investigate the prevalence and risk factors of or facial clefts in Iranian children.Materials and Methods:The present study, was conducted...

Introduction: Cleft lip and palate are among the most common congenital anomalies worldwide. This study was conducted in order to explore the incidence and related factors of cleft lip and/or palate (CL/P) among live births in Mashhad, North-Eastern Iran.   Materials and Methods: In this cross-sectional study, records of 28,519 infants born between March 1982 and March 2011 at three major hospi...

Major histocompatibility complex (MHC) molecules play a key role in cell-mediated immune responses presenting bounded peptides for recognition by the immune system cells. Several in silico methods have been developed to predict the binding affinity of a given peptide to a specific MHC molecule. One of the current state-of-the-art methods for MHC class I is NetMHCpan, which has a core ingredient...

conclusions tissue engineering may open a new window in cleft palate reconstruction. stem cells and growth factors play key roles in this field. results we reported a summary of the key-points concerning cleft palate development, the genes involving this defect, current therapeutic strategies, recently novel aspects, and future advances in treatments for easy and fast understanding of the conce...

background: children with cleft lip and palate generally suffer from inappropriate and inadequate feeding, resulting in insufficient weight gain leading to malnutrition and poor growth. we aimed to evaluate the nutritional and growth status of cleft lip and palate children before and after reconstructive cleft lip and palate surgery. methods: all cleft lip and palate children aging from birth u...

introduction: cleft lips and cleft palates are common congenital abnormalities in children. various chromosomal loci have been suggested to be responsible the development of these abnormalities. the present study was carried out to investigate the association between the suspected genes (methylenetetrahydrofolate reductase [mthfr] a1298c and c677t) that might contribute into the etiology of the...