At the HERA collider at DESY, high energy electron and positron beams interact with proton beams. A review is presented of the variety of ways in which these collisions produce final states containing charm and beauty quarks.

In this paper, the update of proton driven plasma wakefield acceleration (PDPWA) is given. After a brief introduction to the scheme of PDPWA, a future demonstration experiment is discussed. The particle-in-cell simulation results based on the realistic proton beams from the CERN Super Proton Synchrotron (SPS) are presented, followed by a simulation study of proton bunch compression.

Proton acceleration from the interaction of ultra-short laser pulses with thin foil targets at intensities greater than 10(18) W cm(-2) is discussed. An overview of the physical processes giving rise to the generation of protons with multi-MeV energies, in well defined beams with excellent spatial quality, is presented. Specifically, the discussion centres on the influence of laser pulse contra...

The objective of this study is to assess the feasibility of using PRESAGE dosimeters for proton pencil beam dosimetry. Two different formulations of phantom materials were tested for their suitability in characterizing a single proton pencil beam. The dosimetric response of PRESAGE was found to be linear up to 4Gy. First-generation optical CT scanner, OCTOPUS was used to implement dose distribu...

Purpose To investigate narrow, elongated magnetically focused proton beams and compare their properties with passively collimated beams using Monte Carlo simulation. METHODS We performed Geant4 Monte Carlo simulations involving a single quadrapole focusing magnet, thereby creating a flattened beam with an elongated elliptical cross section. The parameters of the magnet were chosen to mimic k=...

PURPOSE Although the Monte Carlo (MC) method allows accurate dose calculation its usage is limited due to long computing time. In order to gain efficiency, a new macro MC (MMC) technique for proton dose calculations in homogeneous materials has been developed. METHODS The macro MC is based on a local to global MC approach. The local simulations using Geant4 consist of mono-energetic proton pe...

BACKGROUND To examine the potential improvement in treatment planning for patients with skull base meningioma using IMRT compared to carbon ion or proton beams with and without a gantry. METHODS Five patients originally treated with photon IMRT were selected for the study. Ion beams were chosen using a horizontal beam or an ion gantry. Intensity controlled raster scanning and the intensity mo...

Introduction: Many study shown the effectiveness dose enhancement with gold nanoparticles (GNPs), especially with low-energy x-rays. Recently, proton beam radiation therapy (PBRT) has attention as a treatment for tumors. The advantage in PBRT, which releases high dose at the controllable Bragg peak position that localized for Au target and the released dose increased in depth....

Physics with neutrino beams has played a crucial role in establishing the standard model and its structure, specifically in leading to the discovery of weak neutral currents and of their properties. Currently, while the physics of neutrinos gives us the first evidence of physics beyond the standard model, the use of neutrinos as probes appears to be the only way of accessing subtle details of t...

We report the initial toxicity data with scanned proton beams at the Italian National Center for Hadrontherapy (CNAO). In September 2011, CNAO commenced patient treatment with scanned proton beams within two prospective Phase II protocols approved by the Italian Health Ministry. Patients with chondrosarcoma or chordoma of the skull base or spine were eligible. By October 2012, 21 patients had c...