hit' protein profile. of different species and strains of nocardia (n.) were compared by using sixlium dodecyl sulphate - polyacryuimidc gel electrophoresis (sds-1'age) of cytoplasmic extract. in the present study n. asteroides, n. hrasilicnsis and n. otitidiscaviartim were examined. it was found that protein profiles

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background: parathyroid hormone is an 84-amino acid peptide secreted by the parathyroid glands. its physiological role is maintenance of normal serum calcium level and bone remodeling. biological activity of this hormone is related to n-terminal 1-34 amino acids. the recombinant form of hormone (1-34) has been approved for treatment of osteoporosis from 2002. in this study, a novel fusion partn...

background: erythropoietin (epo) is a glycoprotein hormone function to regulate the production of red blood cells. deficiency of epo is known to cause anemia in chronically infected renal patients and they require regular blood transfusion. availability of recombinant epo has eliminated the need for blood transfusion and now it is extensively used for the treatment of anemia. glycosylation of e...

Among various practical measures used for restriction of the ground surface settlement in such tunnels driven in soft ground, selection of an appropriate excavation method plays a significant role. In this paper, employing suggested diagram by Yu & Chern, corresponding values of Niayesh tunnel has been inserted into the diagram. Later, two excavation methods namely: central diaphragm and side d...

Background: Coccidiosis caused by Eimeria necatrix has the most economic impact onpoultry production. Micronemal proteins in Eimeria necatrix are thoughtto be critical ligands determining host cell specificity at the time ofinvasion.               OBJECTIVES: Isolation and purification of Eimeria necatrix oocysts from  Khuzestan province of Iran was performed. AcDNA encoding microneme 5 (EnMIC5...

background: cystic fibrosis (cf) is a common autosomal recessive disorder that affects many body systems and is produced by mutations in the cystic fibrosis transmembrane conductance regulator (cftr) gene. cf is also the most frequently inherited disorder in the west. the aim of this study was to detect the mutations in the cftr gene in two iranian families with cf. methods: after dna extractio...

background human immunodeficiency virus (hiv)-1 infection is one of the most important infectious diseases in iran, and common isolates belong to the new crf35_ad subtypes. the gp120 protein, which is located on the surface of the hiv envelope, plays a role in entrance into host cells and immune responses. as there isn’t any clear analysis of the envelope protein of iranian isolates regarding p...

The gap between the number of known protein sequences and the number of known protein structures is rapidly increasing. Computer-based protein structure prediction aims at reducing this sequence-structure gap. Establishing connections between sequence similarity and structural similarity is a prerequisite in the development of protein structure prediction methods. The automated discovery of the...