Surface plasmon resonance (SPR) has emerged as a powerful optical detection technique for studying the binding behaviour of immobilized ligands and analytes in solution. The makes it possible to measure interactions real time with high sensitivity. Over past two decades, SPR become gold standard biomolecular biomedical research drug discovery. that can be studied are diverse include protein–pro...

Appearing as a computational microscope, MD simulation can ‘zoom in’ to atomic resolution to assess detailed interactions of a membrane protein with its surrounding lipids, which play important roles in the stability and function of such proteins. This study has employed the molecular dynamics (MD) simulations, to determine the effect of added DMPC or DMTAP molecules on the structure of D...

conclusions the results indicated that sod-loaded in sln was delivered into deep burned skin layer and induced high enzyme activity through the skin. low particle size, application of lecithin as surfactant and low crystallinity index (ci) percentage were important factors for increasing sod penetration through the burned rat skin. percentage of activity by sln dispersions through rat skin was ...

in this study the plasma levels of lipid peroxidation (lp) products, protein carbonyls and antioxidant capacity of plasma as judged by ferric reducing ability of plasma (frap assay) were compared in adult and weanling rats treated with vitamin k1 phylloquinone).

Sec14, a yeast phosphatidylinositol/phosphatidylcholine transfer protein, functions at the trans-Golgi membranes. It lacks domains involved in protein-protein or protein-lipid interactions and consists solely of Sec14 domain; hence, mechanism underlying function proper sites remains unclear. In this study, we focused on lipid packing membranes evaluated its association with vitro activity. Phos...

While it is known that lipids play an essential role in regulating membrane protein structure and function, remains challenging to identify specific protein–lipid interactions.

background: seaweeds contain significant quantities of lipids, protein, vitamins and minerals. aquavac ergosan contains 1% alginic acid extracted from two brown seaweeds, laminaria digitata and ascophyllum nodosum. both in vivo and in-vitro researches have mainly been focused on the effect of ergosan on fish growth, survival rate, reproductive performance and innate immunity in blood and epider...

In protein film electrochemistry for redox-active membrane proteins, the reconstitution of protein-tethered bilayer lipid membranes (ptBLMs) can maximize their functionality and stability at electrolyte/electrode interfaces. To understand impact protein–lipid interactions on ptBLM formation, we tracked process a in presence or absence transmembrane enzyme cytochrome c-dependent nitric oxide red...