Iron deficiency caused by high pH of saline–alkali soil is a major source abiotic stress affecting plant growth. However, the molecular mechanism underlying iron response in cotton (Gossypium hirsutum) poorly understood. In this study, we investigated impacts at seedling stage and elucidated corresponding regulation network, which centered on hub gene GhbHLH121. induced expression genes with ro...

background: intrauterine growth retardation (iugr) contributes significantly to fetal morbidity and mortality, but its etiology is unknown in most cases. objective: the aim of this study was to examine the association between inherited thrombophilia and iugr. materials and methods: a case-control study was performed in a tertiary referral center (afzalipour hospital) over 2-years period (2010-2...

metabolic myopathies are genetically inherited disorders of muscle energy production that result in skeletal muscle dysfunction. they are a large group of diseases with diverse inborn errors of metabolism, in particular muscle energy production, and including disorders of glycogen (lysosomal and non-lysosomal glycogenoses), lipid (disorders of fatty acid b-oxidation, primary carnitine deficienc...

The coronavirus disease 2019 (COVID-19) or severe acute respiratory syndrome 2 (SARS-CoV-2) pandemic has affected different communities all over the world. A wide spectrum of complications been reported due to COVID-19 infection, among which a hypercoagulability state is one most significant. patient was 44-year-old obese woman with history diabetes, hypothyroidism, cigarette smoking and opium ...

Phosphorus (P) deficiency is a major threat to the crop production, and for understanding response mechanism of plant roots, P stress may facilitate development crops with increased tolerance. Phosphorylation plays critical role in regulation proteins responses biotic abiotic stress; however, its functions starvation/resupply are largely unknown barley ( Hordeum vulgare ) growth. Here, we perfo...

Background: Coagulation Factor VII is a vitamin K-dependent serine protease which has a pivotal role in the initiation of the coagulation cascade. The congenital Factor VII deficiency is a recessive hemorrhagic disorder that occurs due to mutations of F7 gene. In the present study C91S (p.C91S) substitution was detected in a patient with FVII deficiency. This mutation has not b...

This study was carried out to investigate the effects of dietary putrescine (PUT) on broiler’s response fed low crude protein (CP) diets. A total of 192 male day old chicks were fed with four dietary treatments including two levels of PUT (0 and 0.03%) and two levels of CP (normal and low) with factorial combinations. Weekly growth performance, nutrient digestibility and intestinal morphology (...

Coagulation factors belong to a family of plasma glycosylated proteins that should be activated for appropriate blood coagulation. Congenital deficiencies of these factors cause inheritable hemorrhagic diseases. Factor VII (FVII) deficiency is a rare bleeding disorder with variable clinical symptoms. Various mutations have been identified throughout the F7 gene and can affect all the protein do...