OBJECTIVE As propolis is a highly valued bee product, we aimed to verify the quality of aged propolis, investigating their phenolic and flavonoid composition, levels of toxic metals, radical scavenging and antimicrobial activities. MATERIAL AND METHODS Samples of fresh and aged propolis of six different beekeepers, from the same geographical location, were investigated in terms of their pheno...

The newest developments in propolis pharmacological research are summarized. The problem regarding biological studies, caused by the chemical variability of propolis, is discussed. The most important trends and developments in recent propolis research are outlined: biological studies performed with chemically characterized samples, bioassay-guided studies of active principles and comparative bi...

Adulteration of propolis with poplar extract is a serious issue in the bee products market. The aim of this study was to identify marker compounds in adulterated propolis, and examine the transformation of chemical components from poplar buds to propolis. The chemical profiles of poplar extracts and propolis were compared, and a new marker compound, catechol, was isolated and identified from th...

Oxidative stress and synapse dysfunction are the major neurodegenerative damage correlated to cognitive impairment in Alzheimer's disease (AD). We have found that Brazilian green propolis (propolis) improves the cognitive functions of mild cognitive impairment patients living at high altitude; however, mechanism underlying the effects of propolis is unknown. In the present study, we investigate...

INTRODUCTION Because of its chemical diversity, the only way to standardise propolis is to specify multiple standards for different propolis types according to the corresponding chemical profile. So far, this has been done only for European propolis. OBJECTIVE To develop a rapid low-cost spectrophotometric procedure for quantification of bioactive prenylated flavanones in Taiwanese propolis. ...

ETHNOPHARMACOLOGICAL RELEVANCE Propolis is a bee product with numerous biological and pharmacological properties, such as immunomodulatory and anti-inflammatory activities. It has been used in folk medicine as a healthy drink and in food to improve health and prevent inflammatory diseases. However, little is known about its mechanism of action. Thus, the goal of this study was to verify the ant...

Propolis is a honeybee product known for its biological and pharmacological properties for centuries. It has been extensively used in traditional medicine and also, because of its antibacterial, antiseptic, anti-inflammatory, and anesthetic activities, in complementary medicine. Propolis became subject of numerous studies developed and carried out all over the world in order to analyze its chem...

Propolis is a resin formed by a complex chemical composition of substances that bees collect from plants. Since ancient times, propolis has been used in folk medicine, due to its biological properties, that include antimicrobial, anti-inflammatory, antitumoral and immunomodulatory activities. Glioblastoma is the most common human brain tumor. Despite the improvements in GBM standard treatment, ...

Propolis is a resinous hive product Kv bees. The versatile biological activities of propolis, such as its antibacterial, antiviral, fungicidal, anti­ ulcer, immunostimulating, hypotensive and cytosta­ tic properties, as well as its successful clinical applica­ tions [1 — 3] have created an increasing interest in its chemical composition. The last appears to be very complex — the bees collect pr...

Bee propolis is a mixture of plant resins and bee secretions. While bioactivity of honeybee propolis has been reported previously, information is limited on propolis from Australian stingless bees (Tetragonula carbonaria). The aim of this study was to investigate possible vasomodulatory effects of propolis in KCl-precontracted porcine coronary arteries using an ex vivo tissue bath assay. Polar ...