PROPOFOL is commonly used for intensive care unit sedation and prolonged procedures in the adult population where both deep sedation and quick emergence are required. Several recent reports have described a “propofol infusion syndrome,” occurring in both pediatric and adult patients receiving prolonged high-dose infusions of propofol ( 75 g · kg 1 · min 1 24 h). The syndrome is characterized as...

background: early warning of potential damage to spinal cord during major spinal surgery is highly desirable to prevent post-operative neurological deficits. wake-up test is a simple, safe and reliable method of recognition of such a complication, and has been extensively used in many spinal surgical units. the present study is evaluating the remifentanil, propofol versus alfentanil, propofol a...

EDITOR: Propofol is used when deep sedation, immobilization and quick emergence are required and is often used in children during magnetic resonance imaging (MRI) scans. Because the MRI scan is prolonged, a propofol infusion or repetitive small boluses are usually administered. A 13-yr-old patient (weight 44 kg), underwent MRI scan of the head for evaluation of recurrent headaches. The patient ...

: Lipemic blood was noted in the surgical field by a neurosurgeon after 12.5 hours of anesthesia consisting of infusions of propofol (total dose, 14,956 mcg) and remifentanil (total dose, 25,091 mcg). For most of that time, the rate of propofol was 120-160 mcg·kg-1·min-1 and never exceeded 160 mcg·kg-1·min-1. Lipemia was confirmed by allowing a sample of the patient's blood to settle in a syrin...

We present the case of a 7-year old boy with traumatic brain injury who received propofol during 38 h. Thirty-six hours after cessation of propofol infusion asystole occurred. After immediate mechanical and medical resuscitation, unreactive dilated pupils were observed. The following computed tomography scan revealed a generalized brain edema with transtentorial herniation. Prolonged bradyarrhy...