Prolonged activation of the endoplasmic reticulum (ER) stress pathway known as the unfolded protein response (UPR) can lead to cell pathology and subsequent tissue dysfunction. There is now ample evidence that the UPR is chronically activated in atherosclerotic lesional cells, particularly advanced lesional macrophages and endothelial cells. The stressors in advanced lesions that can lead to pr...

A prospective study of 199 patients over a two year period, 1 Jun 90 to 31 May 92 at the Louise Margaret Maternity Wing, Cambridge Military Hospital, Aldershot was undertaken to audit the uptake of an offer of conservative management of prolonged pregnancy to women at 42 weeks gestation. The labour outcomes of patients opting for conservative or induction management plans were recorded and the ...

The use of acupuncture during pregnancy appears to be safe and well tolerated by women in all trimesters. However, there is some debate regarding the use of certain acupuncture points that were historically considered to be forbidden during pregnancy.1 Randomized controlled trials evaluating acupuncture during pregnancy and labor where forbidden points have been used indicate there is no eviden...

root and shoot osmotic and elastic properties of two species of haloxylon aphyllum and h.persicum in response to water stress were studied. the main goal of the study was to determine if the tissuesof two species utilize osmotic adjustment and/or enhance their elastic property during prolonged water stresscondition. the results showed that although tissue elasticity of both species of haloxylon...

THIS paper reviews evidence that the foetus plays a vital role in determining gestation at labour. The hypothesis was not the keystone of our work initially, but evidence of foetal regulation of the myometrium became increasingly apparent during the course of studies on uterine contractility in human pregnancy. Work on induction of labour (Turnbull & Anderson, 1967, 1968a, b) made us aware of t...

Stress, whether daily stress, work stress or traumatic stress, is unhealthy. This lecture covers three recent theoretical approaches in explaining the mechanisms underlying the influence of psychological stress on somatic health. It is argued that stress research should focus less on stressors themselves and put more emphasis on prolonged stress responses. Three mechanisms are identified that c...