Pharmaceutical Industry is striving hard to improve the dissolution of drugs with limited water solubility. One approaches rate poorly soluble solid dispersion. Hence in present research, an attempt was made bioavailability Rosuvastatin by formulating it as a The release calcium dispersion prolonged using HPMC. Eudragit L-100 and PEG-6000 were used carriers. Nine formulations prolonged-release ...

Preparation and characterization of thermoresponsive in-situ forming poloxamer hydrogel for controlled release of Nile red-loaded solid lipid nanoparticles. Nanoparticles (NPs) are cleared rapidly from systemic circulation and do not provide sustained action in most cases. To solve this problem, this investigation introduces an erodible in-situ forming gel system as potential vehicles for prolo...

We obtained data recorded in the Danish medical birth registry on all women with a prolonged pregnancy in the first delivery and in a subsequent delivery, during 1980-94, and a 5% sample of all women with two or more pregnancies recorded in the period 1980-92 (only the first two deliveries were used for analysis). The information on gestational age in the registry was obtained from birth record...

Eggers ED, Klein JS, Moore-Dotson JM. Slow changes in Ca cause prolonged release from GABAergic retinal amacrine cells. J Neurophysiol 110: 709–719, 2013. First published May 8, 2013; doi:10.1152/jn.00913.2012.—The timing of neurotransmitter release from neurons can be modulated by many presynaptic mechanisms. The retina uses synaptic ribbons to mediate slow graded glutamate release from bipola...