Aim: To elucidate clinical features in patients with type 2 diabetes with advanced retinopathy but without nephropathy. Methods: This study examined 1324 patients (784 males and 540 females) with type 2 diabetes mellitus. Diabetic retinopathy was graded according to the International Clinical Classification of Diabetic Retinopathy as no diabetic retinopathy, mild or moderate non-proliferative d...

Background: Anemia may be considered to be an independent risk factor for the development of diabetic retinopathy (DR) in patients with renal failure. The purpose of this study was to investigate the association between blood hemoglobin level and retinopathy in diabetic patients with normal renal function tests.Methods: From 2009 to 2011, 1100 diabetic patients underwent retinal examination. Am...

introduction: diabetic retinopathy (dr) is one of the most serious and most frequent eye diseases in the world and the most common cause of blindness in adults between 20 and 60 years of age. following 15 years of diabetes, about 2% of the diabetic patients are blind and 10% suffer from vision impairment due to dr complications. this paper addresses the automatic detection of microaneurysms (ma...

introduction: diabetic retinopathy is a major cause of blindness and a fundamental cause of disability in diabetic patients in the world. investigation about the quality of life in these patients can help plan for taking nursing measures to prevent or control the disease and improve patients’ quality of life. objective: this study aimed to determine the quality of life in patients with diabetic...

background:diabetic retinopathy (dr) is a sight-threatening microvascular complication of diabetes in which the vascular endothelium is damaged due to oxidative stress and inflammation, and vitreous vegf concentration becomes elevated. the aim of the present study was to assess the association of dr with genetic variations of the mnsod, a major antioxidant enzyme, and vegf, an important mediato...

abstract in this presentation, a case of bilateral choroidal folds in patient with diabetic retinopathy was reported. by our knowledge, this case presentation is the first report of choroidal folds in diabetic retinopathy, which bilateral symmetric and horizontal folds arranged in macula. the thick choroid that is developed in diabetics may be a cause of these folds but the source of difference...

background: diabetes is a common metabolic disorder leading to the development of many complications, among which diabetic retinopathy and macular edema are the most significant. these complications can contribute to blindness if not diagnosed or treated properly, and several studies have been conducted to evaluate the methods for the prevention or slowing down their progression. therefore, ser...

diabetic retinopathy is the lead among causes of blindness in north america. glucose-induced endothelial injury is the most important cause of diabetic retinopathy and other vascular complications. extracellular signal-regulated kinase 5 (erk5), also known as big mitogen-activated protein kinase 1 (bmk1), is a member of mitogen-activated protein kinases (mapk) family. physiologically, it is cri...

purpose : chlamydia pneumonia is a known endothelial pathogen in several vascular diseases including atherosclerosis, age-related macular degeneration and non-arteritic anterior ischemic optic neuropathy. diabetic retinopathy is a retinal vascular disease that may similarly be affected. we serologically investigated the presence of c. pneumonia infection in patients with proliferative diabetic ...