Pelvic organ prolapse (POP) is a common condition in multiparous elderly women and can be associated with hydronephrosis, with or without renal impairment [1]. The renal dysfunction is globally related to the degree of pelvic prolapsed, and its consequences ranges from acute to chronic renal failure and may also lead to end stage renal failure [2]. In this report, we present the case of a negle...

Disturbance of autonomic function is an unusual feature of compression of the cauda equina. A 61 year old man who had complete occlusion of the lumbar spinal canal with compression of the cauda equina from a large centrally prolapsed disc, had spontaneous priapism, precipitated by walking and relieved by resting. This symptom was comparable to claudication by compression of cauda equina. It sub...

Intraductal papillomas (IP) are benign papillary lesions caused by proliferation of mammary ductal epithelium. IP occurs in the breast tissue. Prolapse of IP from nipple can be rarely seen. IPs are generally treated with total excision. A 31-year-old female patient was admitted to our clinic because of a protruded lesion from the nipple of her right breast. On her breast examination, an 8 mm- p...

Cramps in the affected leg are quite common and persistent although sciatic pain may have disappeared completely. A small proportion of patients develop a true recurrent prolapse (prolapse from the same disc) months to years later. This varies in individual statistics, but is probably in the neighbourhood of 4 per cent. to 5 per cent. These recurrent attacks of sciatica, due to a further protru...

Neurology lays many claims to being one of the more precise and scientific branches of medicine but, nevertheless, there have been several neurological conditions almost mediaeval in their conceptions. One of these is a group included under the general heading of the neuritides-namely, sciatic and brachial neuritis and neuralgia. There is now a large body of evidence to show that the humoral, a...

BACKGROUND The precise mechanism of uterine prolapse is poorly understood. There is evidence to suggest that abnormalities of connective tissue structure or its repair mechanism may predispose women to prolapse. METHODS AND RESULTS This immunohistochemical study was performed on paraffin-embedded sections of the cardinal ligaments in an attempt to evaluate differences in the expression of ext...

Objective: Pelvic organ prolapse (POP) remains a great therapeutic challenge with no optimal treatment available. Tissue maintenance and remodeling are performed by fibroblasts, therefore altered cellular functionality may influence tissue quality. In this study, we evaluated functional characteristics of fibroblasts from tissues involved in POP. Study design: To rule out normal ageing tissue d...

LE were hyperrnobile and all but 2 were located at the leaflet coaptation point. All mitra l LE prolapsed 1nto the atrium during systole and the aortic LE prolapsed into the outflow tract during diastole. No LE were noted on the tricusp1d and pulmonic valves. No subject had a cardioembolic event during Jongterm lollow up. Conclusions: 1) LE are common (14%) in subjects with normal hearts. 2) LE...