This review evaluated published data regarding the effects of ghrelin on GI motility using the PubMed database for English articles from 1999 to September 2009. Our strategy was to combine all available information from previous literature, in order to provide a complete structured review on the prokinetic properties of exogenous ghrelin and its potential use for treatment of various GI dysmoti...

Objectives. To assess the efficacy and safety of Liu Jun Zi Tang (LJZT) and Xiang Sha Liu Jun Zi Tang (XSLJZT) for treating functional dyspepsia. Methods. Literature searches were carried out on Medline database, Cochrane Library, CNKI database, Chinese Biomedical Literature database, Wanfang database, and VIP database up to July 2012. Hand search for further references was conducted. Study sel...

Neurology 2012;78:1900–1901 The neural underpinnings for normal and abnormal basal ganglia functions and functional connectivities remain unknown, although several important pieces to the puzzle have emerged over 3 decades. First was the identification of segregated basal ganglia circuits.1 This discovery was closely paralleled by the realization that these circuits communicated through the use...

Gastroparesis is a condition characterized by delayed gastric emptying and the most common known underlying cause is diabetes mellitus. Symptoms include nausea, vomiting, abdominal fullness, and early satiety, which impact to varying degrees on the patient's quality of life. Symptoms and deficits do not necessarily relate to each other, hence despite significant abnormalities in gastric emptyin...

s of all retrieved studies. The full text of the selected studies were then analyzed to ensure that the following inclusion criteria were met: prospective study design, a patient population with a diagnosis of LPR, treatment arm including a prokinetic agent with or without the concomitant use of an antacid therapy (e.g., PPI or H2 antagonist), presence of a comparison arm, and treatment outcome...

OBJECTIVE: To discuss clinical, diagnostic and therapeutic aspects of gastroesophageal reflux. METHOD: We accomplished a literature review of the last 30 years, by means of Lilacs and Medline databases. RESULTS: The gastroesophageal reflux is one of the most frequent causes of medical appointments with pediatric gastroenterologists. It represents a benign condition, characterized by regurgitati...

Duodenum Inversum is a rare congenital anomaly that can produce symptoms due to gastric outlet obstruction. We report a case of a 56-year man who presented with features of delayed gastric emptying owing to duodenum inversum, which was managed successfully by prokinetic agents. The diagnostic modalities and management strategies are presented and the relevant literature has been reviewed.