Background: This study addresses the null hypothesis that there is no expansion of heterotopic ossification (HO) in the elbow beyond what can be seen early on.   Methods: The area of HO was measured on lateral radiographs of 38 consecutive patients that had operative treatment of HO between 2000 and 2013. Measurements from radiographs obtained between 3 to 7 weeks were compared to measurements...

purpose: to determine the effect of trabeculectomy (tx) on cataract formation or progression in glaucoma patients. methods: this controlled clinical trial was performed on 82 eyes of 41 consecutive patients older than 50 years with glaucoma. trabeculectomy was indicated only in one of their eyes and iop in the other eye was controlled with medication. the operated eyes were considered as treatm...

background: studies have shown that zinc and selenium deficiency is common in nonalcoholic fatty liver disease (nafld). however, the effects of zinc and selenium co-supplementation before and/or after disease progression on nafld are not clear enough. the aim of this study was to compare the effects of zinc and selenium co-supplementation before and/or after disease progression on nafld prognos...

Objective: Prediabetes is a state that people have blood glucose levels higher than normal but still not in diabetes range. There is a close relationship between impaired lung function and diabetes mellitus (DM). Reduced lung function can be present before the clinical evidence of diabetes or insulin resistance. Materials and Methods: The total number of subjects in this longitudinal study was ...

Background: The first purpose of this study was to investigate the rate of oral and laryngeal Diadochokinesis (DDK) in Multiple Sclerosis (MS) patients in comparison with healthy people. The second goal was to determine if DDK rate has any relationship with the disease progression. Methods: In this cross-sectional study, two groups were enroll...

background: myopia has different prevalence rate worldwide and there is controversial points about its environmental risk factors. the prevalence of myopia in medical interns atshirazmedicalschool and its probable risk factors were studied.   method: in this retrospective cross-sectional study, three hundred interns (7 th -year medical students) at shiraz university of medical sciences were exa...

Stroke is a leading cause of mortality and morbidity in developed countries and has increased incidence due to progression of average population age. Pharmalogical and mechanical reperfusion therapy, as primary therapeutic approaches, are only applicable to less than 10% of patients with a 50-70% efficacy. but about 90%of patients are severe restricted to these treatments. Glutamate excitotoxic...

Objective(s): Epigenetic regulation of gene expression can be carried out through chromatin remodeling enzymes such as SWI/SNF. Brg1 also known as SMARCA4 is a catalytic subunit of SWI/SNF, which is necessary for MMPs expression. Matrix metalloproteinases (MMPs) are known as important player enzymes during tumor progression and metastasis. Aberrant epigenetic modification of chromatin should be...