The Product Quality Research Institute, in conjunction with the Food and Drug Administration, conducted an anonymous, electronic survey of the biological products manufacturing industry inspected by Team Biologics, with emphasis in obtaining industry input on inspection and compliance aspects of program operations. Representatives from all of the product-specific manufacturing industries inspec...

The importance of nanotechnology in medical technologies, especially biomedical diagnostics, is indubitable. By taking advantages of nanomaterials, many medical diagnostics methods have been developed so far, including electrochemical nanobiosensors. They have been used for quantification of different clinical biomarkers for detecting, screening, or follow up a disease. microRNAs (miRNAs) are o...

OBJECTIVE To determine the seroprevalence of anti-Toxoplasma, anti-Rubella, and anti-Cytomegalovirus (CMV) antibodies among pregnant women receiving prenatal care at Van Training and Research Hospital. MATERIALS AND METHODS In developing countries, various infectious agents encountered in the gestational period are important because they influence both maternal and fetal health. Among these, ...

Staphylococcus intermedius and Staphylococcus pseudintermedius are difficult to distinguish using conventional microbiological methods. Molecular diagnostic tools change our understanding of the epidemiology of these 2 organisms. In this study, we present (1) a detailed review of the current literature on molecular diagnostics and (2) a case series in which misidentification was proven in 1 cas...

A high-quality hemoglobinopathy diagnosis is based on the results of a number of tests including assays for molecular identification of causative mutations. We describe the current diagnostic strategy for the identification of β-thalassemias and hemoglobin (Hb) variants at the International Reference Laboratory for Haemoglobinopathies, Research Centre for Genetic Engineering and Biotechnology (...

Elevated concentrations of homocysteine (Hcy) are associated with a range of disorders. Linearity, imprecision, interference, method comparison, and accuracy were evaluated on the ADVIA Centaur (Siemens Healthcare Diagnostics, Deerfield, IL), ARCHITECT i2000SR (Abbott Diagnostics, Abbott Park, IL), AxSYM (Abbott Diagnostics), and IMMULITE 2000 (Siemens Healthcare Diagnostics) methods and analyz...

Chlamydial Persistence: beyond the Biphasic Paradigm Richard J. Hogan, Sarah A. Mathews, Sanghamitra Mukhopadhyay, James T. Summersgill, and Peter Timms* Infectious Diseases Program and Cooperative Research Centre for Diagnostics, School of Life Sciences, Queensland University of Technology, Brisbane, Australia, and Division of Infectious Diseases, Department of Medicine, University of Louisvil...

Diagnostics and Treatment Sujan C. Reddy, MD; Olivia M. Almendares, MSPH; Wendy Baughman, MSPH; Fernanda C. Lessa, MD; Monica M. Farley, MD; Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA; Georgia Emerging Infections Program, Decatur, GA; Atlanta Research and Education Foundation, Decatur, GA; Atlanta VAMedical Center, Decatur, GA; Division of Healthcare Quali...

background: plasmodium vivax is the most widespread species of plasmodium in humans and causing about 80 million clinical cases annually. this study was under-taken to detect p. vivax in asymptomatic treated vivax malaria patients to trace la-tent/sub-patent malaria infection. method: the venous blood of all detected cases with p. vivax in bashagard, minab and roodan districts in hormozgan prov...

Subclinical infection of vaccinated chickens with a highly pathogenic avian influenza A(H5N2) virus was identified through routine surveillance in China. Investigation suggested that the virus has evolved into multiple genotypes. To better control transmission of the virus, we recommend a strengthened program of education, biosecurity, rapid diagnostics, surveillance, and elimination of infecte...