primary immunodeficiency diseases (pids) are rare but include severe conditions found predominantly in children, most pids have cutaneous manifestations that may be important as early diagnostic features. the purpose of this study was to determine the frequency and nature of cutaneous alterations associated with pids. this article is a cross-sectional study at the department of allergy and clin...

Background: Primary immunodeficiency diseases (PID) occur on average with a frequency of 1: 100 000 the population. In accordance classification PIDS International Union Immunological Societies (IUIS) 9 different groups innate errors immunity are distinguished [1]. The polymorphism clinical picture, difficulties in recognizing PID cause their late diagnosis and associated development irreversib...

primary immunodeficiencies constitute a group of highly complex congenital disorders most of which are characterized by a very poor prognosis. allogeneic hematopoietic stem cell transplantation (hsct) has become an established curative treatment approach in many of these disorders, which may be permanently corrected. in this presentation basic and practical aspects of hsct are presented, with a...