Although glaucoma is a major global cause of blindness, the lack of a uniform definition of the disease in its different forms makes it difficult to assess its public health impact. By considering the common features of glaucoma, we have analysed available data on the three main forms of the disease: congenital/hereditary glaucoma, primary open-angle, and primary angle-closure glaucoma. A simpl...

purpose: to evaluate visual outcomes and intraocular pressure (iop) after single-site phacotrabeculectomy with mitomycin c in patients with senile cataract and primary open angle glaucoma (poag), pseudoexfoliative glaucoma (pxg), or chronic angle closure glaucoma (cacg). methods: in this retrospective study, patients older than 50 years who had significant cataracts (bcva £ 20/60) and uncontrol...

BACKGROUND The strategy of pressure reducing surgery in primary congenital glaucoma has changed over the last decade. Ab externo filtering procedures--for example, trabeculectomy or trabeculotomy combined with trabeculectomy, have now been accepted even as primary intervention. METHODS The authors reviewed 61 eyes in 35 consecutive patients with primary congenital glaucoma, who underwent diff...

PURPOSE To screen the myocilin (MYOC) and forkhead box protein C1 (FOXC1) genes for sequence variations in primary congenital glaucoma (PCG). METHODS Seventy five PCG patients were screened for MYOC variations and 54 cases (negative or heterozygous for cytochrome P4501B1 mutations) for FOXC1 mutations by polymerase chain reaction (PCR) and DNA sequencing. RESULTS Five single nucleotide poly...

PURPOSE To identify and characterize defects using the automated perimetry test in patients with primary congenital glaucoma. METHODS Automated visual fields and charts of 81 eyes (48 patients) with congenital glaucoma were retrospectively analyzed, 15 being normal eyes (group N) and 66 eyes with primary congenital glaucoma (group G). Eyes of group G were grouped in eyes without perimetric ch...

Canine glaucoma encompasses a diverse group of diseases associated with an increase in intraocular pressure that results in retinal ganglion cell death and eventual blindness. Dogs may have congenital, primary, or secondary glaucoma. The diagnosis is made by recognizing clinical signs, interpreting ophthalmic examination findings, and determining intraocular pressure. Identifying the underlying...