Pathological uterine bleeding is one of the significant problems in gynecology. Different aspects abnormal are discussed (classification, causal factors, mechanisms, diagnosis, treatment). Medications assessed according their priorities (haemostatic effect; regulation menstrual cycle). Preferences dufaston underlined: a) It doesn’t characterize by undrogenic, glucocorticoidal and mineralocortic...

The relationship between mean arterial blood pressure (MAP) and hematocrit (Hct) was studied in pre- and postmenopause women in the city of Durango, Mexico. Premenopause women show a negative trend between parameters that is not statistically significant. MAP and Hct are directly related in postmenopause women (p < 0.01). It is proposed that that this MAP/Hct relationship is in part due to diff...

Sex hormone dependency of breast cancer was studied in vitro by examining 3H-thymidine uptake into DNA of breast cancer cells. DMBA induced breast cancer of rats, Shionogi carcinoma 115 and Shionogi carcinoma 42 of mice were studied preliminarily. These 3 kinds of rodent breast cancer showed the same sensitivity to both sex hormones in vitro as has been shown biologically. Subsequently, this se...

Potential determinants of bone mass were investigated in a group of 70 young females (mean age 26.6 years), daughters of women studied in premenopause. Nutritional data, leisure physical activity level, lifestyle habits as well as familial similarities were assessed. The daughters' bone mineral density (BMD), measured by dual-energy absorptiometry, was significantly correlated with their body m...

A double-antibody radioimmunoassay technique has been used to investigate the serum prolactin (hPRL) level in Malay females from premenarche to the postmenopause. The results showed that the hPRL level (mena ± SEM) in the premenarchal, postmenarchal and late pubertal/reproductive subjects were 23.6 ± 2.3,19.1 ± 2.0 and 22.7 ± 1.9 ng] ml respectively. In premenopausal women, hPRL level (11.8 ± 2...

Background Patterns of symptom clustering in midlife women may suggest common underlying mechanisms or may identify women at risk of adverse health outcomes or, conversely, likely to experience healthy aging. This paper assesses symptom clustering in the Study of Women's Health Across the Nation (SWAN) longitudinally by stage of reproductive aging and estimates the probability of women experien...

The urinary progestogen metabolites included in our profiles encompass the primary urinary metabolite, pregnanediol (Pgdiol), and four other more minor metabolites that belong to the pregnane (Allopregnanolone, Allo-pregnanediol) and pregnene (3α-dihydroprogesterone, 20α-dihydroprogesterone) categories. In postmenopausal women the level of pregnanediol is expected to be much lower than in preme...

BACKGROUND/AIMS The aim of this study was to quantitatively measure changes in lipids and lipoproteins during perimenopause and to identify variables related to these changes. METHODS Among women who had three regular health evaluations over a span of 2-4 years, 34 women remained in the premenopausal state, 34 premenopausal women transitioned to the postmenopausal state, and 36 postmenopausal...