AIM Assess influences of demographics and co-morbidities of gout patients with or without diabetes on safety and efficacy of urate-lowering agents. METHODS Post-hoc analysis of 312 diabetic and 1957 non-diabetic gout patients [baseline serum urate levels (sUA) ≥8.0 mg/dl] enrolled in a 6-month randomized controlled trial comparing urate-lowering efficacy (ULE) and safety of daily xanthine oxi...

In {10}, we developed an efficient algorithm for optimizing a class of EQL r"ule-based systems so that they can meet sper.:ified response time eonstr·aints. In this paper, we show that this EQL optimizer with minor modifications can be ~tsed to optimize a class of real-time MRL r"ule-based systems. As a rrwr·e expressive superset of EQL, MRL allows existent-ially quantified as well as univer·.~...

In {10}, we developed an efficient algorithm for optimizing a class of EQL r"ule-based systems so that they can meet sper.:ified response time eonstr·aints. In this paper, we show that this EQL optimizer with minor modifications can be ~tsed to optimize a class of real-time MRL r"ule-based systems. As a rrwr·e expressive superset of EQL, MRL allows existent-ially quantified as well as univer·.~...

This report describes an algoriUun thal computes the configuration space of a polyhedron willi planar motion relative La a fixed polyhedral obstacle. The algorilJlm decomposes the configuration space along Ule orienlation axis into intervals of cross-sections with the same structure. It computes the angles where the srrucrurc changes. In each interval between two changes, it computes the (fi:'\...

Many clinical and laboratory-based studies have been reported for skin rashes which may be due to viral infections, namely pityriasis rosea (PR), Gianotti-Crosti syndrome (GCS), asymmetric periflexural exanthem/unilateral laterothoracic exanthem (APE/ULE), papular-purpuric gloves and socks syndrome (PPGSS), and eruptive pseudo-angiomatosis (EP). Eruptive hypomelanosis (EH) is a newly discovered...

We achieved a 0.5 Hz optical beat note line width with ~ 0.1 Hz/s frequency drift at 972 nm between two external cavity diode lasers independently stabilized to two vertically mounted Fabry-Perot (FP) reference cavities. Vertical FP reference cavities are suspended in mid-plane such that the influence of vertical vibrations to the mirror separation is significantly suppressed. This makes the se...

Some pretreatments that swell and/or open the structure of wood fibers could increase the effectiveness of a biobleaching process, allowing for an industrial application. To this end, a chemical pretreatment (urea, U), a physical pretreatment (refining, R), and their combinations (RU and UR) were optimized to evaluate and compare their enhancement of the LE biobleaching sequence (laccase-mediat...