l-Theanine is a nonprotein amino acid with much beneficial efficacy. We found that intraperitoneal treatment of the mice l-theanine (100 mg/kg/day) enhanced adaptive thermogenesis and induced browning inguinal white adipose tissue (iWAT) elevated expression Prdm16, Ucp1, other thermogenic genes. Meanwhile, administration increased energy expenditure. In vitro studies indicated development brown...