The histone chaperone FACT is an essential and abundant heterodimer found in all eukaryotes. Here we report a crystal structure of the middle domain of the large subunit of FACT (Spt16-M) to reveal a double pleckstrin homology architecture. This structure was found previously in the Pob3-M domain of the small subunit of FACT and in the related histone chaperone Rtt106, although Spt16-M is disti...

In this paper we characterize the radical of an arbitrary‎ ‎submodule $N$ of a finitely generated free module $F$ over a‎ ‎commutatitve ring $R$ with identity‎. ‎Also we study submodules of‎ ‎$F$ which satisfy the radical formula‎. ‎Finally we derive‎ ‎necessary and sufficient conditions for $R$ to be a‎ ‎Pr$ddot{mbox{u}}$fer domain‎, ‎in terms of the radical of a‎ ‎cyclic submodule in $Rbigopl...

An integral domain $D$ is called a emph{locally GCD domain} if $D_{M}$ is aGCD domain for every maximal ideal $M$ of $D$. We study somering-theoretic properties of locally GCD domains. E.g., we show that $%D$ is a locally GCD domain if and only if $aDcap bD$ is locally principalfor all $0neq a,bin D$, and flat overrings of a locally GCD domain arelocally GCD. We also show that the t-class group...

the purpose of the present study is to introduce the sequence space[{l_p}(e,delta) = left{ x = (x_n)_{n = 1}^infty : sum_{n = 1}^infty left| sum_{j in {e_n}} x_j - sum_{j in e_{n + 1}} x_jright| ^p < infty right},]where $e=(e_n)$ is a partition of finite subsets of the positive integers and $pge 1$. the topological properties and inclusion relations of this space are studied. moreover, the prob...

Due to high speed computer networks, the use of digitally formatted data has increased many folds.The digital data can be duplicated and edited with great ease which has led to a need for effectivecopyright protection tools. Digital Watermarking is a technology of embedding watermark withintellectual property rights into images, videos, audios and other multimedia data by a certainalgorithm .Di...

let $d$ be an integral domain and $star$ a semistar operation stable and of finite type on it. we define the semistar dimension (inequality) formula and discover their relations with $star$-universally catenarian domains and $star$-stably strong s-domains. as an application, we give new characterizations of $star$-quasi-pr&amp;quot;{u}fer domains and um$t$ domains in terms of dimension ine...

there is a shortage of quantitative measures for assessing the concept of responsibility as a fundamental construct in medical education, ethics and professionalism in existing literature. this study aimed to develop an instrument for measuring responsibility in both undergraduate and graduate medical students during clinical training. instrument content was based on literature review and mainl...