diabetes mellitus is one of the most common diseases affecting the endocrine system. the prevalence of diabetes mellitus will be increasing in the human population. it is a metabolic disease characterized by chronic escalation of blood glucose and disrupted metabolism of carbohydrates, fats and proteins. this was an experimental study conducted on 40 male wistar rats. this study was carried out...

the essential oil of prangos ferulacea (apiaceae) fruits was obtained by hydrodistillation and analyzed by gas chromatography (gc) and gc-mass spectrometery (ms). among the 39 identified constituents accounting for 99.99% of the total oil, the major components were chrysanthenyl acetate (26.53%), limonene (19.59%), alpha pinene (19.50%), delta-3-carene (6.56%), mesitaldehyde (6.09), and germacr...

      The essential oil of Prangos ferulacea (Apiaceae) fruits was obtained by hydrodistillation and analyzed by gas chromatography (GC) and GC-mass spectrometery (MS). Among the 39 identified constituents accounting for 99.99% of the total oil, the major components were chrysanthenyl acetate (26.53%), limonene (19.59%), alpha pinene (19.50%), delta-3-carene (6.56%), mesitaldehyde (6.0...

Doxorubicin (DOX) is a potent, broad-spectrum chemotherapeutic drug used for treatment of several types of cancers. Despite its effectiveness, it has a wide range of toxic side effects, many of which most likely result from its inherent prooxidant activity. It has been reported that DOX has toxic effects on normal tissues, including brain tissue. In the current study, we investigated the protec...

prangos ferulacea is a plant found in the mediterranean and middle-east regions used as carminative, anti-flatulent, emollient and antibacterial herb. it is believed that the coumarins are responsible for some of known effects of  prangos . in this research the relaxant effects of p. ferulacea coumrin rich extract as well as osthole as its main prenylated coumarins were investigated on rat ileu...

OBJECTIVES Diabetes mellitus manifests itself in a wide variety of complications and the symptoms of this disease are multifactorial. Previous studies proved that this disease is directly related to hyperglycemia and hyperlipidemia. The aim of this study was to investigate the hypoglycemic and hypolipidemic effects of hydroalcoholic extract of Prangos frulacea (L.) Lindl in alloxan-induced diab...