OBJECTIVE To clarify associations between intracerebral hemorrhage (ICH) location and clinical outcomes among participants of the main phase Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial (INTERACT2). METHODS Associations between ICH sites and poor outcomes (death [6] or major disability [3-5] of modified Rankin Scale) and European Quality of Life Scale (EQ-5D) utility ...

A 74-year-old man presented to the ophthalmology outpatient clinic with reduced visual acuity and increasing haziness of vision in his left eye over several months. Seven years previously he had undergone uneventful cataract surgery with phacoemulsification and insertion of a posterior chamber lens (+14.5 dioptres Alcon MA60BM, 6.0 mm optic) in the same eye. There had been no postoperative comp...

Recently, tissue engineering, including 3D bioprinting of the pancreas, has acquired clinical significance and become an outstanding potential method customized treatment for type 1 diabetes mellitus. The study aimed to evaluate function 3D-bioprinted pancreatic petals with islets in murine model. A total 60 NOD-SCID (Nonobese diabetic/severe combined immunodeficiency) mice were used divided in...

Every cataract surgeon should have a game plan for when and how to perform an anterior vitrectomy following posterior capsule rupture. This chapter will review the goals, the indications, and the techniques of an anterior vitrectomy. Understanding and mentally rehearsing these strategies will better prepare cataract surgeons to make correct decisions amidst the stress of an unexpected complicat...

There is a paucity of information in the extant literature regarding the detailed anatomy of the subanconeus (articularis cubiti) muscle. Our current study seeks to elucidate further the presence, morphology, and potential function of this muscle. Eighteen cadaveric upper extremities underwent dissection of their posterior elbow joint capsule with special attention to any fibres attaching to it...

OBJECTIVE To present a new model of posterior capsule opacification (PCO) in mice. METHODS An extracapsular lens extraction was performed in 28 consecutive mice. Animals were humanely killed 0 and 24 hours and 3 and 14 days after surgery. Eyes were enucleated and processed for light microscopy and immunohistochemistry. RESULTS In 20 animals (71%), the eye appeared well healed before death. ...

DOS Times Vol. 12, No. 4 October, 2006 Posterior capsule opacification (PCO) and posterior chamber intraocular lens (PC IOL) decentration still remain two major complications of successful extracapsular cataract surgery (ECCE) or phacoemulsification. Ridley, who performed the first intraocular lens implantation in 1949, himself noted these complications in his earliest patients.7 In his initial...

PURPOSE The German Ophthalmological Society (GOS) recently proposed surgical entry criteria, i.e. 300 cataract surgeries. We herein correlate the surgical hands-on experience with the risk of posterior capsule ruptures in order to assess whether this number is appropriate. METHODS We identified all cataract operations that had been performed at the University Eye Hospital Freiburg since 1995....

AIM To determine the relative risk of a poor visual outcome following posterior capsule rupture during cataract surgery. METHODS Prospective data were collected on consecutive eyes undergoing cataract extraction. The patient's age, preoperative visual acuity, ocular comorbidity, grade of surgeon, and operative complications were documented. The best spectacle corrected visual acuity was recor...