The aim of Chapter 2 is to give an overview of the GPR basic principles and technology. A lot of definitions and often-used terms that will be used throughout the whole work will be explained here. Readers who are familiar with GPR and the demining application can skip parts of this chapter. Section 2.2.4 however can be interesting since a description of the hardware and the design parameters o...

The in vitro activity of telavancin was tested against 743 predominantly antimicrobial-resistant, gram-positive isolates. Telavancin was highly active against methicillin-resistant staphylococci (MIC(90), 0.5 to 1 microg/ml), streptococci (all MICs, < or =0.12 microg/ml), and VanB-type enterococci (all MICs, < or =2 microg/ml). Time-kill studies demonstrated the potent bactericidal activity of ...

A new polyether antibiotic, Ro 21-6150, has been isolated from culture broths of Streptomyces hygroscopicus, strain X-14563. Ro 21-6150 has ionophore properties and is active in vitro against gram-positive bacteria.

Isolation procedures of two new acylphloroglucinols, myrtucommulone-A and myrtucommulone-B, from Myrtus communis leaves are given. Myrtucommulone-A was highly antibacterial against gram-positive bacteria but was not active against gram negatives. The chemical relation to other acylphloroglucinols and the antibacterial activity of the compounds isolated are discussed.

2.2. Assembly Strategies 139 2.2.1. Linear Assembly 139 2.2.2. Convergent Assembly 139 2.2.3. Elaborative and Mixed Assembly Strategies 139 2.2.4. Native Ligation Assembly 140 3. Chemical Glycoprotein Synthesis 143 3.1. Indiscriminate Convergent Glycosylation 143 3.2. Chemoselective and Site-Specific Glycosylation 145 3.3. Site-Selective Glycosylation 147 3.4. Native Ligation Assembly 151 4. En...

We discuss the applicability of the Linear Sampling Method (LSM) to GPR surveys carried out using array-based configurations. Since the images achieved via LSM are known to get worse when using a small number of antennas and a limited aperture, we introduce an analytic tool to foresee the expected LSM performance for a fixed array size and number of antennas. Notably, such a tool allows us to s...

New antibiotics, griseusins A and B were isolated from a strain of Streptomyces griseus. Both antibiotics have a 5-hydroxy-1, 4-naphthoquinone chromophore and their molecular formulae were determined to be C22H20O10 and C22H22O10, respectively. The griseusins are active against gram-positive bacteria.