نتایج جستجو برای: population pharmacokinetics
تعداد نتایج: 720123 فیلتر نتایج به سال:
Objective: To establish a tobramycin dosing schedule for neonates of various gestational ages. Methods: This was a retrospective study with prospective validation. A retrospective study in 470 neonates, with suspected septicemia in the first week of life, was performed. All patients received tobramycin according to the following scheme: neonates with a gestational age of less than 28 weeks rece...
This paper addresses the beginning of toxicokinetics in Spain by group Prof. Bartolomé Ribas 60s last century, as well interdisciplinary collaboration that occurs between academics Royal National Academy Pharmacy (RANF) and more specifically with Rafael Cadórniga, who was a pioneer Biopharmacy Pharmacokinetics studies Spain. scientific is magnificent example work strong interrelationship pharma...
Pharmacokinetics of intravenous lorazepam in pediatric patients with and without status epilepticus.
OBJECTIVE To evaluate the single dose pharmacokinetics of an intravenous dose of lorazepam in pediatric patients treated for status epilepticus (SE) or with a history of SE. STUDY DESIGN Ten hospitals in the Pediatric Emergency Care Applied Research Network enlisted patients 3 months to 17 years with convulsive SE (status cohort) or for a traditional pharmacokinetics study (elective cohort). ...
Population pharmacokinetics of dexmedetomidine during long-term sedation in intensive care patients.
BACKGROUND Dexmedetomidine is a highly selective and potent α(2)-adrenoceptor agonist registered for sedation of patients in intensive care units. There is little information on factors possibly affecting its pharmacokinetics during long drug infusions in critically ill patients. We characterized the pharmacokinetics of dexmedetomidine in critically ill patients during long-term sedation using ...
ôbjective: to investigate the pharmacokinetics (pk) and pk- pharmacodynamic (pd) relationship of methadone in a cohort of outpatients undergoing methadone maintenance treatment (mmt). methods: sixty male patients undergoing mmt with a mean ±sd methadone daily dosage of 58 ± 34 mg were enrolled in this study. â 5-ml blood sample was collected before the daily intake of methadone. âs a pd measure...
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