We discuss the compatibility between reflective PON architectures and the recently defined ITU-T G.989.1 TWDM-PON. Focusing on the upstream, we experimentally demonstrate that, by using burst-mode coherent detection at OLT, reflective PON can achieve the specification target set for TWDM-PON, without requiring precise wavelength accuracy at ONU. Compared to the companion ECOC 2013 paper, we inv...

Orthogonal Frequency Division Multiplexing (OFDM) has been recently selected for a wide range of wireless and wire line applications. Various transmission technologies such as downstream OFDM and upstream single carrier frequency domain equalization (SCFDE) with TDM–PON to achieve flexibility and reduce complexity. So, in order to analyze the performance of OFDM and SCFDE system based on comple...

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT * In previous work, we showed a long-term and concentration-dependent beneficial effect of the non-nucleoside reverse transcriptase inhibitor efavirenz (EFV) on high-density lipoproteins (HDL) in human immunodeficiency virus (HIV)-infected patients. * Furthermore, it has been suggested that instead of the current practice of only measuring HDL-chelestero...

Paraoxonase (PON) is transported primarily on apolipoprotein A-I (apoA-I) -containing high-density lipoprotein (HDL) and is thought to protect against early atherogenic events including low-density lipoprotein (LDL) oxidation and monocyte migration. It has been proposed that apoA-I may be necessary for PON's association with plasma HDL. On the basis of this, we examined the effect of apoA-I on ...

Minocycline prevents oxidative protein modifications and damage in disease models associated with inflammatory glial activation and oxidative stress. Although the drug has been assumed to act by preventing the up-regulation of proinflammatory enzymes, we probed here its direct chemical interaction with reactive oxygen species. The antibiotic did not react with superoxide or (•)NO radicals, but ...

The traffic flow in long-haul dense wavelength division multiplexing fiber networks has surpassed by far the traffic deliverability from/to the access network thus creating what is known as “access bottleneck”. This bottleneck was the result of two major factors, the inherent cost sensitivity of access networks that impedes deployment of new optical technology prior to cost maturity, and the la...

RESEARCH DESIGN AND METHODS — Undiluted vitreous from patients with proliferative diabetic retinopathy (PDR) (n 13) and macular hole (MH) (n 8) was used to determine PON-HCTLase and PON-AREase activity spectrophotometrically. HCTL levels were detected by liquid chromatography–tandem mass spectrometry. In vitro studies were done in primary cultures of bovine retinal capillary endothelial cells (...

Paraoxonase (PON) is a serum enzyme with a wide species distribution. It protects lipoproteins from toxic oxidative modifications and is an antiatherogenic mechanism of major potential. Activity levels of PON are major determinants of the protective function; consequently, factors that influence PON levels are of particular relevance. The present study has identified 3 polymorphisms in the prom...