We have recently concluded from the heat-induced denaturation studies that polyols do not affect deltaG(D) degrees (the Gibbs free energy change (deltaG(D)) at 25 degrees C) of ribonuclease-A and lysozyme at physiological pH and temperature, and their stabilizing effect increases with decrease in pH. Since the estimation of deltaG(D) degrees of proteins from heat-induced denaturation curves req...

The polyols erythritol and adonitol reduced 45 degrees heat killing in asynchronous Chinese hamster ovary cells. Heat protection by glycerol and erythritol increased with the apparent intracellular concentration, as inferred from cell volume measurements, and the number of hydroxyl groups per alcohol molecule. The nonlinear tetrahydroxy alcohol pentaerythritol did not protect but sensitized to ...

Debaryomyces hansenii is a halotolerant yeast that produces and assimilates a wide variety of polyols. In this work we evaluate polyol transport in D. hansenii CBS 767, detecting the occurrence of polyol/H(+) (and sugar/H(+)) symporter activity, through the transient extracellular alkalinization of unbuffered starved cell suspensions. From the D. hansenii genome database, we selected nine ORFs ...

The sustainability of the polymeric materials has become a fundamental challenge; therefore, development new biobased formulations gained increasing interest. Thermoset polyurethanes (PURs) present high performance and are competitive solution for structural composites. However, polyols used in PUR synthesis typically from petrochemical origin. Nowdays, broad range is available market, but ther...

The gustatory responses of the Mongolian gerbil were tested with 12 sugar alcohols. The electrophysiological effectiveness of the linear polyols as gustatory stimulants increased as the length of the carbon chain increased from 2 to 5. Six and 7 carbon acyclic polyols were no more effective than the pentitols. By comparison myoinositol, a cyclic polyol, was more effective in evoking a response....

background sugar alcohol erythritol is a non-caloric sweetener, non-cariogenic, and safe for diabetics because of no change to blood glucose and insulin levels after oral administration. erythritol cannot be degraded by any enzymatic systems and must be eliminated from the blood through the kidney. objectives: the aim of this study was production and optimization of erythritol from glucose by y...

Herein, we present the design, synthesis, and characterization of fully degradable, hybrid, star-branched dendritic polyols. First multiarmed polyphosphazenes were prepared as a star-branched scaffold which upon functionalization produced globular branched hydroxyl-functionalized polymers with over 1700 peripheral functional end groups. These polyols with unique branched architectures could be ...

Polyols can be synthesized from carbohydrates in bioor chemo-catalytic way. The conversion of polyols with two hydroxyl groups in 1,4-positions, for example 1,4-butanediol, results in furan derivatives. In contrast, during the dehydration of diols with two vicinal hydroxyl groups, for example, 1,2-propaneand 1,2-butanediol, aldehydes or ketones are formed [1] . This will be presented exemplaril...

Gold nanoparticles are easily obtained by a range of room temperature processes. In particular, polyols-based syntheses performed in alkaline conditions without the need for surfactants lead to small size around 10 nm diameter. While highly viscous polyols, such as glycerol, have been most studied polyols with which perform reaction, use alternative alcohols lower viscosity could benefit proces...