Introduction: Bismuth-based nanoparticles having high atomic number and electron density, besides of being utilized as CT contrast agent, stand as a strongly proposed method for dose enhancement in radiotherapy. Embedded nanoparticle in polymer gel dosimeter poses the first step to assess the dose enhancement capability in nanoparticles. To this end, MAGICA gel dosimeter, whic...

Background: Gold nanoparticles (GNPs) are among the most promising radiosensitive materials in radiotherapy. Studying the effective sensitizing factors such as nanoparticle size, concentration, surface features, radiation energy and cell type can help to optimize the effect and possible clinical application of GNPs in radiation therapy. In this study, the radiation sensitive polymer gel was use...

The BANG polymer gel dosimeter was used to evaluate 3D absorbed dose distributions in tissue delivered with Gamma Knife stereotactic radiosurgery systems. We compared dose distributions calculated with Leksell GammaPlan (LGP) treatment-planning software with dose distributions measured with the polymer gel dosimeter for single-shot irradiations. Head-sized spherical glass vessels filled with th...

Polymer gel dosimetry undertaken on a multislice CT scanner provides an alternative method to conventional dosimetry measurements. Polymer gel dosimeters were used to measure CT radiation doses and compared to TLD and ionization chamber measurements in different diameter phantoms. CTDI was investigated for each of these phantoms for a range of mAs (100-400 mAs), tube voltage (100-135 kV) and no...

Abstract Three different dosimetry systems were prepared based on diphenyl thiocarbazone (DTH) dye: polymer films made with, poly(vinyl alcohol), DTH liquid dosimeter and gel dosimeter. All the received several gamma doses. The three analyzing by UV–Vis spectrophotometery before after irradiation. effective dose range in linear part of these is between 1–10 kGy, 0.3–2 50–200 Gy. dosimeters reli...

Changes in the linear attenuation coefficient of polymer gel dosimeters post-irradiation enable the imaging of dose distributions by x-ray computed tomography (CT). Various compositions of polymer gel dosimeters manufactured from acrylamide (AA), and N,N'-methylene-bis-acrylamide (BIS) comonomers and gelatin or agarose gelling agents were investigated. This work shows that increasing the comono...

This study extends the 'zero scan' method for CT imaging of polymer gel dosimeters to include multislice acquisitions. Multislice CT images consisting of 24 slices of 1.2 mm thickness were acquired of an irradiated polymer gel dosimeter and processed with the zero scan technique. The results demonstrate that zero scan-based gel readout can be successfully applied to generate a three-dimensional...

Introduction: The PAGAT polymer gel dosimeter melts at 30 ˚C and even at room temperature during the summer, so it needs to be kept in a cool place such as a refrigerator. To increase the stability of the PAGAT gel, different amounts of agarose were added to the PAGAT gel composition and the PAGATA gel was manufactured. Material and Methods: The PAGATA gel vials were irradiated using a Co-60 ma...

A feasibility study of proton beam PET/CT off-line quantitative dosimetry using polymer gels is presented. A newly developed proton-sensitive polymer gel dosimeter (BANG®3-Pro2) is used as a dosimeter and a tissue-equivalent phantom medium for this study. We explore a new approach to correlating measured proton 3-dimensional (3D) dose distributions directly to measured positron emission from in...