Background VEGF gene has been reported to be related with many diseases and recurrent pregnancy loss in various studies. VEGF polymorphisms are risk factors for pregnancy losses, and generally studies report only women’s genetic analyses. To evaluate the association between VEGF A C405G, C460T, C936T and C2578A polymorphisms and spontaneous abortion, we studied the genotypes of spontaneously a...

objectives the aim of this study was to evaluate the efficacy, safety, and tolerability of sofosbuvir and ribavirin in ldlt recipients with recurrent hcv genotype 4. patients and methods thirty-nine egyptian ldlt recipients were treated for recurrent hcv after ldlt with nucleos(t)ide analog ns5b polymerase inhibitor, sofosbuvir, and ribavirin without pegylated interferon for 6 months (november ...

background: this study was conducted to determine of molecular epidemiology of the giardia lamblia by pcr-rflp method in tehran, capital of iran. methods: thirty eight stool samples were randomly selected from 125 patients diagnosed with giardiasis using microscopy in tehran. dna extraction of some samples were performed by phenol/chloroform/isoamyl alcohol method and to raise the sen­sitivity ...

results phylogenetic analysis of the partial ns5b region demonstrated the relatedness of isolate fsm165 to the new subtype reported from iran in 2006. moreover, some core/e1 and ns5b sequences that had a high level of similarity with fsm165 isolate were found through searching the hcv database. these sequences were previously either misclassified or could not be accurately classified. phylogene...

background: endometriosis is a female health disorder that occurs when cells from the lining of the uterus grow in other areas of the body. the cause of endometriosis is unknown. objective: the purpose of this study was to investigate tp53 gene codon 72 polymorphism in women with endometriosis and compared it with healthy samples in isfahan. materials and methods: we undertook a case-control st...

background: interaction between killer cell immunoglobulin-like receptors (kir) and human leukocyte antigen (hla) class i molecules is important for regulation of natural killer (nk) cell function. objective: the aim of this study was to investigate the impact of compound kir-hla genotype on susceptibility to acute leukemia. methods: cohorts of iranian patients with acute myeloid leukemia (aml;...

blastocystis hominis is a protozoan parasite which mainly found in human fecal samples both from symptomatic patients and asymptomatic population in developing countries. in this study we reported a patient referred to gi clinic with abdominal pain, nausea, vomiting, fever for 2 or 3 days and passed watery stools because of blastocystis sp. subtype 2 infection.

background: molecular epidemiology of measles virus (mv) is important, not only to measure the success of measles vaccination programs but also to monitor the circulation and elimination of the virus worldwide. in this study, we compared mv obtained from patients before the 2003 mass vaccination mr campaign and viruses detected after 2003 until 2008 in iran. methods: the nucleoprotein (n) gene ...