A workshop on the Human Health Impacts of Halogenated Biphenyls and Related Compounds was held to assess the state of current research on these chemicals and to make recommendations for future studies. Participants discussed results from laboratory animal experiments on PCBs, PBBs, dioxins, and dibenzofurans which demonstrate a common mode of toxicological action while also revealing large vari...

Most of the studies on polybrominated biphenyls (PBB) have been on toxicological evaluations. Very few studies have dealt with their persistence and concentration potential in several environmental matrices such as soil, sediments, and biota as a function of matrix properties. The understanding of these relationships will form some basis for assessing the characteristics of the contaminant's be...

Michigan Chemical Corporation, St. Louis, Michigan manufactured PBB from 1970 until November 20, 1974. Studies in 1974 showed significant quantities of PBB in effluent discharged from the facility and in water, fish, ducks, and sediments from the Pine River. Fish uptake rates and bioconcentration factors were estimated. Followup surveys over the three year period since the termination of PBB pr...