The asymmetric synthesis of the orthogonally funtionalised compounds tert-butyl 2-N-benzyl-N-alpha-methylbenzylamino-5-methoxycarbonylmethylcyclopentane- 1-carboxylate and methyl 2-N-benzyl-N-alpha-methylbenzylamino-5-carboxymethylcyclo- pentane-1-carboxylate by a domino reaction of tert-butyl methyl (E,E)-octa-2,6- diendioate with lithium N-alpha-methylbenzyl-N-benzylamide initiated by a Micha...

Platinum, palladium, and copper catalysts supported on precipitated silica have been studied for the hydrodeoxygenation and hydrogenation of 2-methyl-2-pentenal in the 200–400 C temperature range. The activity follows the order Pt > Pd > Cu. It has been found that at low temperatures, Pt and Pd are primarily active for the hydrogenation of the C@C bond to make 2-methyl-pentanal, with some decar...

purpose: to compare the results of three-piece and one- piece hydrophobic acrylic posterior chamber intraocular lens (iol) with poly methyl metacrylate (pmma) iol implanted during lensectomy, posterior capsulotomy and anterior vitrectomy for congenital or developmental cataract. methods: this is a historical cohort study conducted on patients with congenital or developmental cataract who underw...

A new class of quinoline derivatives containing pyrazoline-5-one and pyrazole moiety (3a-j and 4a-j) have been synthesized by condensation of various oxobutyrates/pentane-2,4-dione derivatives with 8-quinolinoxyacetic acid hydrazide. Elemental analysis, IR, H NMR and mass spectral data support the structures of the newly synthesized compounds. The synthesized compounds have been evaluated for t...