Background and aims: Chlorpyrifos (CPF) is an insecticide that widely used in the world. The purpose of this research was to investigate effect 4-week aerobic exercise eugenol supplementation on phosphatidylinositol-3-kinases/protein kinase/mammalian target rapamycin (Pi3K/AKT/mTOR) pathway skeletal muscle male rats poisoned with CPF. Methods: Overall, 12-week-old female were experimental resea...

Organophosphate (OP) and carbamate (CM) are the most commonly used pesticides against insects. Little is known regarding the relationship between dementia and acute OP and CM poisoning. A nationwide population-based cohort study was conducted from the National Health Insurance Research Database in Taiwan. The incidence and relative risk of dementia were assessed in patients hospitalized for acu...

Currently, liver transplantation is the only option for patients with end-stage liver disease. In Brazil, the mortality rate on the waiting list is about 25%. Multiple strategies to expand the donor pool are being pursed, however, grafts from poisoned donors are rarely used. This report documents successful liver, kidney and heart transplantations from four female donors who suffered brain deat...

1. Liver tissue showing fatty degeneration obtained from animals poisoned with phosphorus or chloroform contains a decreased amount of esterase. 2. The serum of animals poisoned with phosphorus or chloroform has a high esterase activity. 3. The increased amount of esterase in the serum is not derived from the disintegrating liver cells as the esterase in the blood of the hepatic vein is less th...

To determine the risk of secondary poisoning for animals preying on sub-lethally poisoned brushtail possums, captive possums were treated with near-lethal doses of sodium monofluoroacetate (1080) or brodifacoum, and toxicant concentrations in blood and tissue were monitored over time. Sodium monofluoroacetate was rapidly eliminated from the blood (within three days). Brodifacoum was retained in...

Objective: To study the antioxidant status and the extent of oxidative stress in patients with organophosphorus insecticide (OPI) poisoning before and after specific treatment. Material and Methods: The study was conducted in eighty-four OPI poisoned patients. Superoxide dismutase (SOD) and malonyl aldehyde (MDA) levels were estimated as an index of antioxidant status and oxidative stress respe...

Sir, There may well be a place for emetics in the treatment of children who have ingested poison, as advocated by David Reid (1970). However, on the evidence at present available, it is quite unjustifiable to conclude that emesis is superior to gastric lavage in terms of safety or effectiveness. The risks of properly performed lavage are frequently exaggerated. Bleeding does occur in approximat...

In 2005 Canadians received a shock. Environmental Defence tested the blood of average Canadians for a wide range of pollutants in the fi rst test of its kind. Testing covered a wide range of chemicals found in individuals from across Canada. Toxic chemicals were found to contaminate Canadians no matter where they lived in the country, how old they were, or what they did for a living. Dr. Rick S...

With the establishment of the inadequate efficiency of atropines and oximes in reducing morbidity and mortality of patients poisoned by organophosphates, more attention is given to using other methods such as Fresh Frozen Plasma (FFP) as a bioscavenger to mop up organophosphate toxins. This randomized clinical trial was conducted on 56 organophosphate poisoned patients who were randomly assigne...