Lesch Alcoholism Typology (LAT) is one of the most widely used clinical typologies of alcohol addiction. Study tested whether introduction of LAT software in clinical practice leaded to improved outcomes and reduced costs. Retrospective matched-pairs case-control cost comparison study was conducted at the Regional Addiction Center of the University Clinic in Serbia involving 250 patients during...

The present paper is a continuation of a series of comprehensive taxonomic treatments of cercosporoid fungi (formerly Cercospora s. lat.), belonging to Mycosphaerellaceae (Ascomycota). This fifth contribution of this series proceeds with treatments of cercosporoid fungi on dicots and comprises species occurring on hosts belonging to the families Anacardiaceae and Annonaceae, which are described...

The herpes simplex virus type 1 (HSV-1) latency-associated transcript (LAT) is abundantly expressed in latently infected trigeminal ganglionic sensory neurons. Expression of the first 1.5 kb of LAT coding sequences is sufficient for the wild-type reactivation phenotype in small animal models of infection. The ability of the first 1.5 kb of LAT coding sequences to inhibit apoptosis is important ...

The serine/threonine kinase LKB1 is a tumour suppressor that regulates cell growth, polarity, and proliferation in many different cell types. We previously demonstrated that LKB1 controls thymocyte survival via regulation of AMPK activation. In this study, we show that LKB1 was also involved in thymocyte positive selection through regulation of T cell receptor (TCR) signalling. Both Lck-Cre- an...

Carbon (C), nitrogen (N), and phosphorus (P) stoichiometry is a key indicator of nutrient utilization in plants, C/N/P ratios are related to the life histories adaptation strategies tree species. However, no consensus has been reached on how leaf stoichiometric characteristics affected by forest type stand ages. The relationships between geographical, meteorological, soil factors also remain po...

The serine/threonine kinase LKB1 is a tumour suppressor that regulates cell growth, polarity, and proliferation in many different cell types. We previously demonstrated that LKB1 controls thymocyte survival via regulation of AMPK activation. In this study, we show that LKB1 was also involved in thymocyte positive selection through regulation of T cell receptor (TCR) signalling. Both LckCreand C...

The linker for activation of T cells (LAT), the linker for activation of B cells (LAB), and the linker for activation of X cells (LAX) form a family of transmembrane adaptor proteins widely expressed in lymphocytes. These scaffolding proteins have multiple binding motifs that, when phosphorylated, bind the SH2 domain of the cytosolic adaptor Grb2. Thus, the valence of LAT, LAB and LAX for Grb2 ...

Formosiepyrisvietnamensis sp. n. (Hymenoptera: Bethylidae) is described based on material collected from Da Lat, southern Vietnam. This is the first record of Formosiepyris Terayama from Vietnam. The new species can be distinguished from other Formosiepyris species by a narrow and rounded clypeus; a mandible with three teeth; a second metasomal tergite having small, sparsely distributed punctur...

The present paper continues a series of comprehensive taxonomic treatments of cercosporoid fungi (formerly Cercospora s. lat.), belonging to the Mycosphaerellaceae (Ascomycota). The fourth contribution of this series initiates treatments of cercosporoid fungi on dicots and comprises species occurring on hosts belonging the the families Acanthaceae, Actinidiaceae, Adoxaceae, Aizoaceae, Altingiac...

a KPJ Healthcare University College, School of Medicine, Department of Otorhinolaryngology, Head & Neck Surgery, Selangor, Malaysia b KPJ Klang Specialist Hospital/KPJ Healthcare University College, Ear, Nose & Throat -Head & Neck Consultant Clinic, Selangor, Malaysia c University Kebangsaan Malaysia Medical Center, Department of Otorhinolaryngology, Head & Neck Surgery, Kuala Lumpur, Malaysia ...