Key words: (1) compensatory lung growth; (2) pneumonectomy; (3) lung metastasis; (4) adenovirus-mediated gene therapy; and (5) anti-angiogenesis.Abstract Growth of solid tumor metastases is critically dependent on angiogenesis. We hypothesized that an " angiogenic-rich " milieu, as in pneumonectomy-induced lung growth, would be conducive to growth of pulmonary metastases, and that transfer of a...

OBJECTIVES The study aimed to compare in-hospital, 30-day and non-cancer-related 6-month death rates in a series of right and left pneumonectomy cases matched according to functional parameters. METHODS A retrospective study was conducted on a series of 263 non-small cell lung cancer patients who underwent pneumonectomy. Left and right pneumonectomy cases were matched according to propensity ...

Objectives: To explore the perioperative nursing care for lung cancer patients undergoing total pneumonectomy, and to promote their rehabilitation. Methods: We will provide preoperative assessment education in aspects of respiratory function, diet, psychology continuous postoperative management about posture, fluid, help diagnosed with squamous cell carcinoma underwent pneumonectomy reduce comp...

Regeneration of the gas exchange area by induction of neoalveolarisation would greatly improve therapeutic options in destructive pulmonary diseases. Unilateral pneumonectomy is an established model to remove defined portions of gas exchange area and study mechanisms of compensatory lung growth. The question of whether new alveoli are added to the residual lung after pneumonectomy in mice was a...

Pneumonectomy is associated with significant postoperative mortality. This study was undertaken to develop and validate a risk model of mortality following pneumonectomy. We reviewed our prospective database and identified 774 pneumonectomies from a total of 7792 consecutive anatomical lung resections in the years 2003 to 2010 (rate of pneumonectomy: 9.9%). Based on data from 542 pneumonectomie...

BACKGROUND Sleeve lobectomy for lung cancer in close proximity to or involving the carina is widely accepted. Operative morbidity and mortality rates, recurrence, and survival rates have varied considerably across studies. MATERIALS AND METHODS From March of 2005 to July of 2010, sleeve lobectomy was performed in 19 patients and pneumonectomy was performed in 20 patients. In this paper, the r...

Retrospective single institution analysis of all patients undergoing sleeve lobectomy or pneumonectomy between 2000 and 2005. Seventy-eight patients underwent pneumonectomy (65 patients <70 years, 13 patients >70 years) and 69 sleeve lobectomy (50 patients <70 years, 19 patients >70 years). Pre-existing co-morbidity, surgical indication and induction therapy was similarly distributed between tr...

OBJECTIVE Perioperative morbidity and mortality in patients receiving pneumonectomy because of non-small cell lung cancer (NSCLC) remains quite high. The aim of this study is to identify risk factors to minimize perioperative mortality and morbidity. PATIENTS AND METHOD The results of 156 Patients who received pneumonectomy between 1995 and 2004 were reviewed retrospectively. All patients had...

OBJECTIVE To compare survival, morbidity, and mortality rates for a series of patients who underwent either bronchoplastic sleeve lobectomy or pneumonectomy to treat non-small cell lung cancer (NSCLC). PATIENTS AND METHOD We reviewed the clinical records for patients who underwent sleeve lobectomy or pneumonectomy for NSCLC from January 1994 through December 2003. RESULTS From January 1994 ...

Post-pneumonectomy spontaneous pneumothorax is fortunately a very rare condition. We describe herein a late spontaneous right pneumothorax case occurring in a post-pneumonectomy patient and treated by thoracotomic bullectomy.