objective(s): a box-behnken design was used for evaluation of eudragit coated diclofenac pellets. the purpose of this work was to optimize diclofenac pellets to improve the physicochemical properties using experimental design. materials and methods: diclofenac was loaded onto the non-pareil beads using conventional coating pan. film coating of pellets was done at the same pan. the effect of pla...

This paper focuses on the improvement of a relaxor ferroelectric terpolymer, i.e., poly (vinylidene fluoride-trifluoroethylene-chlorofluoroethylene) [P(VDF-TrFE-CFE)], filled with a bis(2-ethylhexyl) phthalate (DEHP). The developed material gave rise to a significantly increased longitudinal electrostrictive strain, as well as an increased mechanical energy density under a relatively low electr...

Di(2-ethylhexyl)phthalate, commonly referred to as DEHP, is predominantly used as a plasticizer in the production of flexible polyvinyl chloride (PVC) products. At least 95% of DEHP produced is used as a plasticizer for PVC. PVC is made flexible by addition of plasticizers and is used in many common items such as wall coverings, tablecloths, floor tiles, furniture upholstery, shower curtains, g...

Abstract. Research is devoted to the possibility of obtaining a composition based on microdispersed ash additive and plasticizer. Waste from sewage sludge used. They are formed at thermal power plants. Such ashes distinguished by presence large amount organic matter low calcium content. Therefore, they rarely used in construction. The activation waste fuel use plasticizer can improve performanc...

in recent decades, most of researchers in pharmaceutical preparations have focused increasingly on new formulations that control the site and amount of drug delivery. mucoadhesive dosage forms are available for systemic or local treatment. the mucoadhesive dosage forms are introduced in various forms such as tablets, gels, ointments, patches and polymeric films. for buccal wound and injury the ...

the purpose of this work was to study the effect of various permeation enhancers on the permeation of salbutamol sulphate (ss) buccal patches through buccal mucosa in order to improve the bioavailability by avoiding the first pass metabolism in the liver and possibly in the gut wall and also achieve a better therapeutic effect. the influence of various permeation enhancers, such as dimethyl sul...

Studies were conducted to determine the mechanism of drug release from pellets coated with an ethylcellulose-based pseudolatex widely accepted for use as a sustained release coating for pharmaceuticals. Possible mechanisms for release include solution/diffusion through the continuous polymer phase and/or plasticizer channels, diffusion through aqueous pores and osmotically driven release throug...