objective: plasmodium falciparum chloroquine resistance is a major problem in malaria endemic areas. single nucleotide polymorphisms in pfcrt and pfmdr1 genes are known to be associated with chloroquine resistance in some parts of the world. the major goal of the present study was to detect the five single nucleotide polymorphisms in pfmdr1 gene and one single nucleotide polymorphisms in pfcrt ...

background: plasmodium vivax is the most widespread species of plasmodium in humans and causing about 80 million clinical cases annually. this study was under-taken to detect p. vivax in asymptomatic treated vivax malaria patients to trace la-tent/sub-patent malaria infection. method: the venous blood of all detected cases with p. vivax in bashagard, minab and roodan districts in hormozgan prov...

one of the most important infectious diseases in the world is malaria. about half of the world populations are exposed to the risk of the disease. the program for controlling and eradication of malaria has been being conducted in our country since many years ago. one of the public health problems in the endemic and non-endemic countries is imported malaria which can cause new and permanent infe...

The most common types of blood protozoa in chickens are from the phylum Apicomplexa, including Plasmodium, Leucocytozoon and Haemoproteus. Blood protozoan diseases can cause decreased egg production, stunting death poultry farms. This study aims to identify calculate prevalence infection casted off laying sold at Wonokromo Market, Surabaya City. One hundred samples were taken by purposive sampl...

background& objectives: inspite of intensive worldwide efforts to reduce its transmission, malaria remains the most serious and widespread protozoal infection of humans. it is a protozoan disease transmitted by the bite of infected female anopheles mosquito. malaria has long featured prominently in the grey area between parasitology and hematology. this study has been performed to evaluate ...

Background Malaria is one of tropical and semi-tropical and vector-borne parasitic diseases produced by the protozoan parasites of the genus and species Plasmodium. The aim of this study was to assess the epidemiology and the factors associated with the malaria in children in Sistan and Baluchistan province in 2013-2016. Materials and Methods This cross-sectional study was conducted between Mar...

Malaria, one of the world's most common diseases, is caused by the intracellular protozoan parasite known as Plasmodium. In this study, we have determined the evolutionary relationship of two single-copy proteins, circumsporozoite protein (CSP) and merozoite surface protein-1 (MSP-1), among Plasmodium species using various bioinformatics tools and softwares. These two proteins are major blood s...

Understanding drugs’ mechanism of action is integral to successful antimalarial drug development. Recent advances in chemoproteomic methods have created an avenue globally profile targets the Plasmodium parasites that cause malaria. Some these strategies even allow direct measurement living intracellular parasites. The cover feature highlights achievement probing drug–protein interactome intact...

background: asymptomatic malaria infection provides a reservoir of parasites, causing the persistence of malaria transmission. it accounts an important challenge for successful management of the control, elimination, and eradication programmes in any malaria-endemic region. this investigation was designed to assess the presence and the prevalence of asymptomatic carriers in iranshahr district o...