نتایج جستجو برای: plasminogen activator

تعداد نتایج: 52174  

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 1998
R Swiercz J D Wolfe A Zaher J Jankun

Malignant tumors contrast with benign ones in their ability to invade adjacent tissue and to metastasize. The urokinase plasminogen activator is a proteolytic enzyme that can facilitate these processes. In many carcinomas, the concentration of the urokinase plasminogen activator system is high. The high expression of these enzymes is related to tumor grade. In this study, we have investigated w...

Journal: :anesthesiology and pain medicine 0
masoumeh nouri department of clinical pharmacy, faculty of pharmacy, tehran university of medical sciences, tehran, iran arezoo ahmadi department of anesthesiology and critical care medicine, faculty of medicine, sina hospital, tehran university of medical sciences, tehran, iran farhad etezadi department of anesthesiology and critical care medicine, faculty of medicine, sina hospital, tehran university of medical sciences, tehran, iran elchin barzegar department of clinical pharmacy, faculty of pharmacy, tehran university of medical sciences, tehran, iran mojtaba mojtahedzadeh department of clinical pharmacy, faculty of pharmacy, tehran university of medical sciences, tehran, iran; department of clinical pharmacy, faculty of pharmacy, tehran university of medical sciences, tehran, iran. tel: +98-2188012501

results the infusion group had a lower plasma pai-1 level compared to the subcutaneous group at day 7 (11.3 ± 1.6 vs. 16.5 ± 4.2; p = 0.003). the urinary ngal level was lower in the infusion group at day 2 (131.3 ± 11.9 vs. 151.2 ± 20.6; p = 0.014); however, at day 7 the ngal level was decreased in the subcutaneous group as much as the infusion group and there was no significant difference betw...

Journal: :Hypertension 2001
L Sironi A M Calvio L Arnaboldi A Corsini A Parolari M de Gasparo E Tremoli L Mussoni

Previous studies have shown that angiotensin II stimulates the synthesis of plasminogen activator inhibitor-1 in cultured vascular cells, which suggests that activation of the renin-angiotensin system may impair fibrinolysis. We have investigated the effects of angiotensin II and of valsartan, a recently developed angiotensin II antagonist that is highly specific and selective for the angiotens...

Journal: :Biochemical and biophysical research communications 1980
P A Barouski T D Gelehrter

Glucocorticoids decrease the plasminogen activator activity of rat hepatoma cells through production of an inhibitor. We have examined the dexamethasone regulation of plasminogen activator in anucleate rat hepatoma cells to investigate the role of the nucleus in the steroid regulation of this membrane-associated phenomenon. Dexamethasone did not affect either the intraor extra-cellular plasmino...

Journal: :archives of clinical infectious diseases 0
mitra barati pediatric infectious diseases research centre, iran university of medical sciences, tehran, ir iran; pediatric infectious diseases research centre, iran university of medical sciences, tehran, ir iran. tel: +98-9121065388 mehdi shekarabi pediatric infectious diseases research centre, iran university of medical sciences, tehran, ir iran saeed chobkar department of internal medicine, iran university of medical sciences,tehran, ir iran mahshid talebi-taher antimicrobial resistance research center, iran university of medical sciences, tehran, ir iran newsha farhadi medical faculty, shahed university, tehran, iran

background sepsis is one of the most important causes of morbidity and mortality in the intensive care units (icus). it is difficult to accurately differentiate sepsis from similar diseases rapidly. therefore, it becomes critical to identify any biomarker with the ability of differentiation between sepsis and nonsepsis conditions. the urokinase plasminogen activator receptor has been implicated...

Journal: :Gut 1972
A Jedrychowski S P Parbhoo P Hillenbrand

Plasminogen activator activity was studied in bile and perfusate during extracorporeal pig liver perfusion. Plasminogen activator activity in bile was up to 58 times greater than in perfusate. A high level of plasminogen activator activity in bile was also found after the addition of urokinase to the perfusate. These results suggest that bile is the main route of active excretion of plasminogen...

Myxoma may cause systemic embolization and frequently presents as ischemic stroke. There has been debates whether it is safe to use recombinant tissue plasminogen activator (rt-PA) in patients with cardiac myxoma who are presented with ischemic stroke at emergency department. we describe a young case of atrial myxoma with initial presentation of acute cerebral infarction symptoms who was treate...

Journal: :Kidney International Reports 2022

To analyze the expression of soluble urokinase-type plasminogen activator receptor (suPAR) in plasma, and to explore value plasma suPAR, urinary neutrophil gelatinase associated lipid carrier protein (NGAL) kidney injury molecule-1 (KIM-1) early diagnosis adult with cardiac surgery-associated acute (CSA-AKI).

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