The composition of the plasma lipoproteins is continuously modified during their intravascular metabolism, as a result of a dynamic exchange and net transfer of lipids between particles or between particles and cells. Specialized proteins, the plasma lipid transfer proteins, facilitate the transfer and exchange of phospholipids, cholesteryl esters, and triglycerides between the lipoproteins. Al...

Lipoproteins, isolated by sequential flotation at densities 1.006, 1.019, 1.063, and 1.21, were examined for their ability to inhibit human lymphocytes stimulated by allogeneic cells and by lectins (phytohemagglutinin-P and concanavalin A). All the classes of normal plasma lipoproteins inhibited lymphoproliferation when peripheral blood lymphocytes were cultured in autologous, heterologous, or ...

Rat liver ribosomes in uifro incorporated labeled amino acids into proteins which showed the immunological behavior of the plasma lipoproteins. The presence of carrier lipoprotein or carrier lipid was required for the isolation and ultracentrifugal purification of immunologically reactive, labeled low and high density lipoproteins. The identity of the lipoproteins was further characterized by s...

1. The appearance of exogenous cholesterol in free cholesterol and ester cholesterol of plasma chylomicra, very-low-density (VLD), low-density (LD) and high-density (HD) lipoproteins was studied in unanaesthetized rabbits after ingestion of a meal containing 5% fat and 0.08% [(3)H]cholesterol. 2. The specific radioactivity of ester cholesterol of VLD lipoproteins reached the highest value of an...

Objective(s) The purpose of the present study was to evaluate the effect of Ramadan fasting and weight-lifting training on plasma volume, glucose, and lipids profile of male weight-lifter. Materials and Methods Forty male weight-lifters were recruited and divided into 4 groups (n=10 each) and as the following groups: control (C), fasting (F), training (T) and fasting-training (F-T). The T an...

Incubation of phosphatidylcholine vesicles with isolated high density lipoproteins (HDL) or with whole plasma results in transfer of phospholipid into HDL. To investigate the mechanisms of this process, small unilamellar vesicles of egg phosphatidylcholine were incubated with human HDL3 (d 1.125 to 1.210 g/ml) or with plasma and were subsequently analyzed by density gradient ultracentrifugation...

Lipoproteins were isolated from plasma of man, dog, rabbit, rat, and chicken by ultracentrifugation in continuous density gradients using the B14 titanium and B15 titanium zonal rotors. Both the VLDL and the LDL of human plasma were separated easily from the HDL and from the other more plentiful plasma proteins by centrifugation for only 1 or 2 hr in the B14 or B15 rotor, respectively. Satisfac...