نتایج جستجو برای: plackett burman pb design

تعداد نتایج: 995823  

2014
Snehal Ingale Sonam Kalyani Urvish Chhaya

234 Application of Statistical Design to Optimize Culture Medium for Xylanase Production by Bacillus pumilus AB-1 Snehal Ingale, Sonam Kalyani 1 and Urvish Chhaya Ashok and Rita Patel Institute of Integrated Study and Research in Biotechnology & Allied Sciences, New Vallabh Vidyanagar-388120, Gujarat, India Natubhai V. Patel College of Pure and Applied Sciences, Vallabh Vidyanagar-388120, Gujar...

2016
Shobha Rani

Methotrexate (MTX) being the widely used biologic agent is used to treat severe and/or disabling psoriasis but precipitates various side effects on oral therapy. Encapsulating methotrexate in flexible liposomes for delivery through skin could lead to better therapeutic action and reduce side effects. In order to screen out the various factors during liposome formulation development, Plackett Bu...

Journal: :Journal of chromatographic science 2011
Aline Bergesch Barth Gabriela Bolfe de Oliveira Marcelo Donadel Malesuik Clésio Soldatelli Paim Nadia Maria Volpato

A stability-indicating liquid chromatography method for the determination of the antifungal agent butenafine hydrochloride (BTF) in a cream was developed and validated using the Plackett-Burman experimental design for robustness evaluation. Also, the drug photodegradation kinetics was determined. The analytical column was operated with acetonitrile, methanol and a solution of triethylamine 0.3%...

2011
RAJAMANICKAM USHA KANJANA MALA CHIDAMBARAM KULANDAISAMY VENIL MUTHUSAMY PALANISWAMY

Marine actinomycetes were isolated from sediment samples collected from Pitchavaram mangrove ecosystem situated along the southeast coast of India. Maximum actinomycete population was noted in rhizosphere region. About 38% of the isolates produced L-asparaginase. One potential strain KUA106 produced higher level of enzyme using tryptone glucose yeast extract medium. Based on the studied phenoty...

2013
Yuanfeng Wu Jianwei Mao Lehe Mei Shiwang Liu

Background: Natural sulforaphane (SF) has been of increasing interest for nutraceutical and pharmaceutical industries due to its anti-cancer effect. The main objective of the present work was to optimize the production of SF from broccoli seed using response surface methodology. Results: Three major factors (hydrolysis time, water volume and ethyl acetate volume) were screened out through Plack...

2008
Sandip B. Bankar Mahesh V. Bule Rekha S. Singhal Laxmi Ananthanarayan

A number of nutritional factors influencing glucose oxidase (EC 1.1.3.4) production by Aspergillus niger NCIM 545 were studied. The synthesis of glucose oxidase by A. niger was investigated in two steps using submerged fermentation at 30±2 °C and 180 rpm for 96 h. Primarily, nutritional components were selected by onefactor-at-a-time method, and the significance of each component with respect t...

2013
P Pratheebaa R Periasamy T Palvannan

In the present study, Plackett–Burman design (PBD) followed by response surface methodology (RSM) was used to optimize the culture medium composition for laccase production from Pleurotus ostreatus IMI 395545. Influence of carbon, nitrogen (sources) and inducer were evaluated by Plackett–Burman design. The factors that induce positive effect on enzyme production were further optimized using cen...

Journal: :Sakarya University Journal of Science 2021

This study aimed to investigate new bacterial sources with the ability produce inulinase and optimize fermentation conditions for production. The production was carried out using newly isolated Bacillus licheniformis velezensis among identified sixteen strains. four essential variables incubation time (1-3 days), temperature (25-40°C), pH (5-7), Wheat Bran (WB) level (1-5%) determined by Placke...

2015
A. Sharma R. Tewari

Biofuels production has come forth as a future technology to combat the problem of depleting fossil fuels. Bio-based ethanol production from enzymatic lignocellulosic biomass degradation serves an efficient method and catching the eye of scientific community. High cost of the enzyme is the major obstacle in preventing the commercialization of this process. Thus main objective of the present stu...

2015
Noura El-Ahmady El-Naggar Hassan Moawad Nancy M. El-Shweihy Sara M. El-Ewasy

Among the antitumor drugs, bacterial enzyme L-asparaginase has been employed as the most effective chemotherapeutic agent in pediatric oncotherapy especially for acute lymphoblastic leukemia. Glutaminase free L-asparaginase producing actinomycetes were isolated from soil samples collected from Egypt. Among them, a potential culture, strain NEAE-119, was selected and identified on the basis of m...

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