نتایج جستجو برای: placental transfer
تعداد نتایج: 311164 فیلتر نتایج به سال:
1 Division of Clinical Pharmacology and Toxicology, the Hospital for Sick Children, Toronto, Ontario, Canada, 2 Department of Pharmaceutical Sciences, University of Toronto, Toronto, Ontario, Canada, 3 Division of Endocrinology, Mount Sinai Hospital, Department of Medicine, University of Toronto, Toronto, Ontario, Canada, and 4 Department of Laboratory Medicine and Pathobiology, University of T...
Offspring of obese and diabetic mothers are at increased risk of being born with excess adiposity as a consequence of their intrauterine environment. Excessive fetal fat accretion reflects additional placental nutrient transfer, suggesting an effect of the maternal environment on placental function. High plasma levels of particular nutrients in obese and diabetic mothers are likely to be the im...
INTRODUCTION During pregnancy, immunoglobulin G (IgG) is transferred from the mother to the fetus, providing protection from disease in early infancy. Plasmodium falciparum infections may reduce maternofetal antibody transfer efficiency, but mechanisms remain unclear. METHODS Mother-cord paired serum samples collected at delivery from Papua New Guinea (PNG) and the Thailand-Myanmar Border Are...
BACKGROUND Studies among HIV-1-infected women have demonstrated reduced placental transfer of IgG antibodies against measles and other pathogens. As a result, infants born to women with HIV-1 infection may not acquire adequate passive immunity in utero and this could contribute to high infant morbidity and mortality in this vulnerable population. METHODS To determine factors associated with d...
Assisted reproductive technologies (ART) are associated with several complications including low birth weight, abnormal placentation and increased risk for rare imprinting disorders. Indeed, experimental studies demonstrate ART procedures independent of existing infertility induce epigenetic perturbations in the embryo and extraembryonic tissues. To test the hypothesis that these epigenetic per...
Recent studies measuring fetal cerebral oxygen and glucose uptake in sheep indicate that the requirements of the fetal brain are comparable to those of the adult (Makowski, Schneider, Tsoulos, Colwill, Battaglia & Meschia, 1972). Since oxygen and glucose contents of arterial blood perfusing the fetal head are considerably less than in the adult animal, there would appear to be a low margin of s...
AIM To determine the influence of placental malaria, maternal HIV infection, and maternal hypergammaglobulinaemia on transplacental IgG antibody transfer. METHODS One hundred and eighty materno-neonatal pairs from a Malawian population were assessed. Cord and maternal serum samples were tested for total serum IgG antibody titres using nephelometry, and for specific IgG antibody titres to Stre...
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